Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076497 | 0.75 | FKBP1A (0.46) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7077516 | 0.73 | HTT (0.42) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7077521 | 0.72 | POLB (0.46) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29316045 | 0.72 | ALDH1A1 (0.59) | ALDH1A1FKBP1AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL29317054 | 0.72 | ALDH1A1 (0.59) | ALDH1A1FKBP1AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL11022250 | 0.68 | PSEN1 (0.56) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3717708 | 0.67 | ALDH1A1 (0.71) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3710420 | 0.67 | ALDH1A1 (0.71) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7125741 | 0.67 | MGLL (0.43) | ALDH1A1NPSR1MGLLMAPTMEN1 | |
| SCHEMBL6003121 | 0.67 | TSHR (0.53) | ALDH1A1NPSR1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003525203-A | — | — | 2003-08-26 | — | — | JP | claimed |
| EP-1163213-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2001-12-19 | — | — | EP | claimed |
| WO-2000056704-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2000-09-28 | — | — | WO | claimed |