SCHEMBL7125867

SCHEMBL7125867

Cn1c2c(c3ccccc31)-c1ccccc1C2CC1=CC=CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
NTRK1 P04629 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7119482 0.81 WDR5 (0.35) GPR3NTRK1
SCHEMBL7124307 0.79 GPR3 (0.41) GPR3NTRK1
SCHEMBL7126885 0.79 GPR3 (0.41) GPR3NTRK1
SCHEMBL3994179 0.76 HTR2A (0.42) GPR3
SCHEMBL8439620 0.74 HTR2A (0.41) GPR3
Hydrochloric Acid SCHEMBL6560684 0.73 HTR2A (0.40) GPR3
Hydrochloric Acid SCHEMBL7642652 0.73 HTR2A (0.40) GPR3
Hydrochloric Acid SCHEMBL7939927 0.73 HTR2A (0.40) GPR3
Hydrochloric Acid SCHEMBL6065450 0.73 HTR2A (0.40) GPR3
Hydrochloric Acid SCHEMBL9066834 0.73 HTR2A (0.40) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030148877-A1 Metallocenes and catalysts for olefin-polymerisation BASELL TECHNOLOGY COMPANY BV (NL) 2003-08-07 US disclosed
EP-0952978-B1 METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP disclosed
US-6451724-B1 BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE BASELL TECHNOLOGY COMPANY BV (NL) 2002-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030148877-A1 Metallocenes and catalysts for olefin-polymerisation MT-CO1, CPNE4, MT-CO3 GPR3 3696/4885NTRK1 3468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.