Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095508 | 0.85 | CES1 (0.55) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| SCHEMBL6447785 | 0.77 | KEAP1 (0.50) | ALDH1A1ALOX12HPGDGAASMN1; SMN2 | |
| SCHEMBL649122 | 0.76 | CES1 (0.46) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| SCHEMBL28200225 | 0.76 | CES1 (0.58) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| SCHEMBL13461367 | 0.76 | CES1 (0.46) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| SCHEMBL41907 | 0.76 | CES1 (0.58) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| SCHEMBL28267372 | 0.74 | CES1 (0.70) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL27862997 | 0.74 | CES1 (0.56) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| SCHEMBL27564061 | 0.74 | CES1 (0.56) | CES1CES2AKR1B1ALDH1A1KMT2A | |
| Bromide SCHEMBL11497452 | 0.74 | CES1 (0.56) | CES1CES2AKR1B1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | TOKUYAMA CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| WO-2025070122-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-04-03 | — | — | WO | disclosed |
| WO-2025057814-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-03-20 | — | — | WO | disclosed |
| WO-2025041624-A1 | PHOTOCHROMIC COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-02-27 | — | — | WO | disclosed |
| WO-2025041625-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-02-27 | — | — | WO | disclosed |
| WO-2025028365-A1 | PHOTOCHROMIC COMPOUND, PHENOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | 株式会社トクヤマ | 2025-02-06 | — | — | WO | disclosed |
| WO-2024202087-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2024-10-03 | — | — | WO | disclosed |
| WO-2024202086-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | 株式会社トクヤマ | 2024-10-03 | — | — | WO | disclosed |
| US-20230280500-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC CURABLE COMPOSITION, CURED BODY, LENS AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2023-09-07 | — | — | US | disclosed |
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |
| EP-1674460-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2006-06-28 | — | — | EP | disclosed |
| US-7048876-B2 | Photochromic compound exhibits absorption bands in two wavelength regions of 440 to 500 nm and 570 to 630 nm. | TOKUYAMA CORPORATION (JP) | 2006-05-23 | — | — | US | disclosed |
| US-20040094753-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1394156-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0778276-B1 | Photochromic chromene derivatives | TOKUYAMA CORP (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0696582-B1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORP (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5808100-A | DURABILITY | TOKUYAMA CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0778276-A1 | Photochromic chromene derivatives | TOKUYAMA CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | CCNL2, CRY2, CRY1 | CES1 4399/4885CES2 3088/4885AKR1B1 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.