Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.45 |
| ▸ | NOS2 | P35228 | 3/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 10/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13216883 | 0.85 | NOS3 (0.37) | NOS3NOS2NOS1LNPEPCYP1A2 | |
| SCHEMBL7124872 | 0.81 | NOS3 (0.46) | NOS3NOS2NOS1ALDH1A1CYP1A2 | |
| SCHEMBL873263 | 0.81 | NOS3 (0.43) | NOS3NOS2NOS1GABRPGABRD | |
| SCHEMBL10496086 | 0.79 | NOS3 (0.47) | NOS3NOS2NOS1ALDH1A1GABRP | |
| SCHEMBL23742549 | 0.78 | NOS3 (0.33) | NOS3NOS2NOS1ALDH1A1 | |
| SCHEMBL20288204 | 0.76 | NOS3 (0.35) | NOS3NOS2NOS1ALDH1A1CYP1A2 | |
| SCHEMBL31651921 | 0.76 | GRIN2D (0.38) | NOS3NOS2NOS1ALDH1A1GABRP | |
| SCHEMBL9124919 | 0.76 | NOS3 (0.44) | NOS3NOS2NOS1ALDH1A1GABRP | |
| SCHEMBL18031196 | 0.76 | NOS3 (0.70) | NOS3NOS2NOS1GABRPGABRD | |
| SCHEMBL13841384 | 0.76 | NOS3 (0.44) | NOS3NOS2NOS1ALDH1A1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064989-A1 | Inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064989-A1 | Inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction | MYH10, MYLK, MKI67 | NOS3 416/4885NOS2 1820/4885NOS1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.