Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30021400 | 0.87 | NOS3 (0.42) | NOS3NOS2NOS1DHFRGABRP | |
| SCHEMBL16414472 | 0.84 | NOS3 (0.44) | NOS3NOS2NOS1DHFRGRIN2D | |
| SCHEMBL7126232 | 0.81 | NOS3 (0.45) | NOS3NOS2NOS1GABRPGABRD | |
| SCHEMBL31651921 | 0.79 | GRIN2D (0.38) | NOS3NOS2NOS1DHFRGRIN2D | |
| SCHEMBL12343957 | 0.76 | MAPT (0.39) | NOS3NOS2NOS1POLB | |
| SCHEMBL20869190 | 0.76 | P2RX3 (0.46) | NOS3NOS1PDE10A | |
| SCHEMBL7117731 | 0.75 | NOS3 (0.48) | NOS3NOS2NOS1DHFRGRIN2D | |
| SCHEMBL7220089 | 0.74 | NOS3 (0.36) | NOS3NOS2NOS1PDE10A | |
| SCHEMBL7213409 | 0.74 | MAPK1 (0.39) | NOS3NOS2NOS1PDE10A | |
| SCHEMBL11335296 | 0.74 | PDXK (0.35) | NOS3NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796800-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2017-10-24 | — | — | US | claimed |
| US-20160108153-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2016-04-21 | — | — | US | claimed |
| US-9249244-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2016-02-02 | — | — | US | claimed |
| EP-2619233-A1 | PROCESS FOR PRODUCING POLYDIENES | Bridgestone Corporation (JP) | 2013-07-31 | — | — | EP | claimed |
| CN-103154044-A | Process for producing polydienes | BRIDGESTONE CORP | 2013-06-12 | — | — | CN | claimed |
| WO-2012040026-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | WO | claimed |
| US-10066076-B1 | Method for preparing conjugated diene polymer, composition comprising the same and tire comprising the composition | LG CHEM, LTD. (KR) | 2018-09-04 | — | — | US | disclosed |
| US-20180244892-A1 | METHOD FOR PREPARING CONJUGATED DIENE POLYMER, COMPOSITION COMPRISING THE SAME AND TIRE COMPRISING THE COMPOSITION | LG CHEM, LTD. (KR) | 2018-08-30 | — | — | US | disclosed |
| US-9988515-B2 | Method for preparing conjugated diene polymer, composition comprising the same and tire comprising the composition | LG CHEM, LTD. (KR) | 2018-06-05 | — | — | US | disclosed |
| US-9796800-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2017-10-24 | — | — | US | disclosed |
| EP-2826793-B1 | METHOD FOR PREPARING CONJUGATED DIENE-BASED POLYMER, COMPOSITION CONTAINING POLYMER, AND TIRE COMPRISING COMPOSITION | LG CHEMICAL LTD (KR) | 2017-08-16 | — | — | EP | disclosed |
| EP-2658886-B1 | BULK POLYMERIZATION OF CONJUGATED DIENES USING A NICKEL-BASED CATALYST SYSTEM | BRIDGESTONE CORP (JP) | 2017-03-08 | — | — | EP | disclosed |
| US-9546227-B2 | Bulk polymerization of conjugated dienes using a nickel-based catalyst system | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| WO-2012092547-A1 | BULK POLYMERIZATION OF CONJUGATED DIENES USING A NICKEL-BASED CATALYST SYSTEM | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012092551-A1 | BULK POLYMERIZATION OF CONJUGATED DIENES USING A NICKEL-BASED CATALYST SYSTEM | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012040026-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | WO | disclosed |
| US-20030064989-A1 | Inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2003-04-03 | — | — | US | disclosed |
| EP-0725095-B1 | Process for producing a polymer of vinylic compounds | KURARAY CO (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-5708103-A | Process for producing a polymer of vinylic compounds | KURARAY CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725095-A1 | Process for producing a polymer of vinylic compounds | KURARAY CO., LTD. (JP) | 1996-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064989-A1 | Inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction | MYH10, MYLK, MKI67 | NOS3 416/4885NOS2 1820/4885NOS1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.