SCHEMBL712632

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6936798	0.93	RAB9A (0.55)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL7152515	0.90	ESR1 (0.53)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL4586692	0.88	TDP1 (0.63)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL7152510	0.87	MAPT (0.56)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL30150476	0.85	LMNA (0.62)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL25782363	0.83	RAB9A (0.60)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL714123	0.82	TDP1 (0.57)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL28216122	0.82	LMNA (0.59)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL23754766	0.81	LMNA (0.58)	LMNARAB9ANPC1TDP1ALDH1A1
	SCHEMBL15869128	0.81	LMNA (0.68)	LMNARAB9ANPC1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.