Acridine

Acridine

SCHEMBL7126489

CCCCCS(N)(=O)=O.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 11/20 0.50
ALDH1A1 P00352 4/20 0.47
GLA P06280 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
ACHE P22303 1/20 0.47
HTR3A P46098 1/20 0.41
CA2 P00918 1/20 0.40
HTT P42858 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GPBAR1 Q8TDU6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL28232031 0.81 ALDH1A1 (0.65) TLR8ALDH1A1GLAMAPTHPGD
Acridine SCHEMBL27681561 0.81 ALDH1A1 (0.65) TLR8ALDH1A1GLAMAPTHPGD
Acridine SCHEMBL28205217 0.79 ALDH1A1 (0.62) TLR8ALDH1A1GLAMAPTHPGD
Acridine SCHEMBL29014290 0.79 ALDH1A1 (0.68) TLR8ALDH1A1GLAMAPTHPGD
Acridine SCHEMBL2140243 0.77 ALDH1A1 (0.71) TLR8ALDH1A1GLAMAPTHPGD
Acridine SCHEMBL21408390 0.77 ALDH1A1 (0.54) TLR8ALDH1A1GLAMAPTHPGD
Biphenyl SCHEMBL1725384 0.76 CA2 (0.47) CA2
Acridine SCHEMBL27710856 0.75 ALDH1A1 (0.56) TLR8ALDH1A1GLAMAPTHPGD
Acridine SCHEMBL25416084 0.73 ALDH1A1 (0.54) TLR8ALDH1A1GLAMAPTHPGD
Anthraquinone SCHEMBL9174074 0.73 PTPN1 (0.49) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6258551-B1 Method for carrying out an immunoassay in a multiphase system DADE BEHRING MARBURG GMBH (DE) 2001-07-10 US claimed
US-6013457-A Method for carrying out an immunoassay in a multiphase system DADE BEHRING MARBURG GMBH (DE) 2000-01-11 US claimed
EP-3121590-B1 LIGHTGUIDE AGGREGATE INSPECTION DEVICE AND INSPECTION METHOD UNIVERSAL BIO RESEARCH CO LTD (JP) 2023-08-02 EP disclosed
US-10139348-B2 Lightguide aggregate inspection device and inspection method of the same UNIVERSAL BIO RESEARCH CO., LTD. (JP) 2018-11-27 US disclosed
US-20180172597-A1 LIGHTGUIDE AGGREGATE INSPECTION DEVICE AND INSPECTION METHOD OF THE SAME UNIVERSAL BIO RESEARCH CO., LTD. (JP) 2018-06-21 US disclosed
EP-3121590-A1 LIGHTGUIDE AGGREGATE INSPECTION DEVICE AND INSPECTION METHOD Universal Bio Research Co., Ltd. (JP) 2017-01-25 EP disclosed
US-20030068635-A1 Determination of an analyte using two labels BOEHRINGER MANNHEIM GMBH 2003-04-10 US disclosed
US-6447999-B1 TTHE COMBINATION OF TWO MECHANISMS OF DETECTION IN A SINGLE DEVICE YIELDS A METHOD WHICH ALLOWS THE SIMPLE QUANTIFICATION OF ANALYTE DETERMINATIONS. ROCHE DIAGNOSTICS GMBH (DE) 2002-09-10 US disclosed
EP-0912765-B1 DETERMINATION OF ANALYTES BY MEANS OF TWO MARKERS ROCHE DIAGNOSTICS GMBH (DE) 2002-07-31 EP disclosed
EP-0912765-A1 DETERMINATION OF ANALYTES BY MEANS OF TWO MARKERS Roche Diagnostics GmbH (DE) 1999-05-06 EP disclosed
WO-1998001578-A1 DETERMINATION OF ANALYTES BY MEANS OF TWO MARKERS BOEHRINGER MANNHEIM GMBH (DE) 1998-01-15 WO disclosed