Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773903 | 0.87 | CYP2A6 (0.48) | ALDH1A1CYP2A6ACHECYP1A2HPGD | |
| Iodide SCHEMBL3905319 | 0.86 | CYP2A6 (0.47) | ALDH1A1CYP2A6ACHECYP1A2HPGD | |
| SCHEMBL9696995 | 0.79 | ALDH1A1 (0.40) | ALDH1A1CYP2A6ACHECYP1A2HPGD | |
| SCHEMBL4076563 | 0.70 | ALDH1A1 (0.50) | ALDH1A1CYP2A6ACHECYP1A2HPGD | |
| SCHEMBL28257139 | 0.69 | CYP1A2 (0.47) | CYP2A6ACHECYP1A2MAPTMEN1 | |
| SCHEMBL278568 | 0.69 | ATM (0.56) | ACHEHIF1AMAPTHTTKDM4E | |
| SCHEMBL29464772 | 0.69 | ATM (0.56) | ACHEHIF1AMAPTHTTKDM4E | |
| SCHEMBL28273210 | 0.69 | CYP1A2 (0.40) | CYP2A6ACHECYP1A2MAPTHTT | |
| Hydrochloric Acid SCHEMBL10713131 | 0.68 | ACHE (0.50) | ALDH1A1ACHECYP1A2HPGDHSD17B10 | |
| SCHEMBL9990610 | 0.67 | ALDH1A1 (0.50) | ALDH1A1CYP2A6ACHECYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627659-B1 | Methods of decreasing the effects of oxidative stress using N-acetylcysteine | ZAMBON GROUP S.P.A. (IT) | 2003-09-30 | — | — | US | disclosed |
| US-20030139472-A1 | Use of N-acetylcysteine for the preparation of a medicament suitable for the intravenous administration to prevent oxidative stress in dialysed patients | ZAMBON GROUP S.P.A. (IT) | 2003-07-24 | — | — | US | disclosed |
| EP-1171112-A2 | USE OF N-ACETYLCYSTEINE FOR THE PREPARATION OF A MEDICAMENT SUITABLE FOR THE INTRAVENOUS ADMINISTRATION TO PREVENT OXIDATIVE STRESS IN DIALYSED PATIENTS | ZAMBON GROUP S.p.A. (IT) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000064421-A2 | USE OF N-ACETYLCYSTEINE FOR THE PREPARATION OF A MEDICAMENT SUITABLE FOR THE INTRAVENOUS ADMINISTRATION TO PREVENT OXIDATIVE STRESS IN DIALYSED PATIENTS | ZAMBON GROUP S.P.A. (IT) | 2000-11-02 | — | — | WO | disclosed |
| US-5434085-A | Method and apparatus for superoxide and nitric oxide measurement | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-07-18 | — | — | US | disclosed |
| WO-1992016648-A1 | CHEMILUMINESCENT TEST FOR MICROORGANISMS | ENVIRONMENTAL TEST SYSTEMS, INC. (US) | 1992-10-01 | — | — | WO | disclosed |