Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619926 | 0.69 | MAPK1 (0.50) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL4812367 | 0.67 | TSHR (0.73) | MAPK1L3MBTL1GAAALDH1A1KDM4E | |
| SCHEMBL7180056 | 0.66 | MAPK1 (0.70) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL8485302 | 0.66 | MAPK1 (0.53) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL5247202 | 0.63 | L3MBTL1 (0.46) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL27592567 | 0.63 | MAPK1 (0.70) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL4617096 | 0.61 | MAPK1 (0.68) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL50688 | 0.61 | MAPK1 (1.00) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL51046 | 0.61 | MAPK1 (0.68) | MAPK1CA1CA2CA9L3MBTL1 | |
| SCHEMBL11679037 | 0.61 | MAPK1 (0.68) | MAPK1CA1CA2CA9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294691-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096305-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |