Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Purine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 2/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Purine SCHEMBL2120554 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL29365913 | 0.98 | — | — | |
| Purine SCHEMBL6421380 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL3158 | 0.98 | — | — | |
| Purine SCHEMBL29703771 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL30862524 | 0.98 | — | — | |
| Purine SCHEMBL6438164 | 0.95 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL712798 | 0.95 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL619820 | 0.95 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A | |
| Purine SCHEMBL31212689 | 0.95 | ALDH1A1 (0.45) | ALDH1A1KDM4EPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115732084-A | Construction method, evaluation model and evaluation method of lactation woman iodine intake evaluation model | 天津医科大学 | 2023-03-03 | — | — | CN | claimed |
| US-20250074915-A1 | DIORGANYL DISELENIDE-CLUBBED QUATERNARY PURINES AS CORROSION INHIBITORS | King Faisal University (SA) | 2025-03-06 | — | — | US | disclosed |
| US-20250074914-A1 | DIORGANYL DISELENIDE-CLUBBED QUATERNARY PURINES AS CORROSION INHIBITORS | King Faisal University (SA) | 2025-03-06 | — | — | US | disclosed |
| US-12234243-B1 | Diorganyl diselenide-clubbed quaternary purines as corrosion inhibitors | King Faisal University (SA) | 2025-02-25 | — | — | US | disclosed |
| US-12221451-B1 | Diorganyl diselenide-clubbed quaternary purines as corrosion inhibitors | King Faisal University (SA) | 2025-02-11 | — | — | US | disclosed |
| CN-115732084-A | Construction method, evaluation model and evaluation method of lactation woman iodine intake evaluation model | 天津医科大学 | 2023-03-03 | — | — | CN | disclosed |
| WO-2022255220-A1 | PROCESSING SOLUTION, METHOD FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND METHOD FOR MANUFACTURING SEMICONDUCTOR ELEMENT | 富士フイルム株式会社 | 2022-12-08 | — | — | WO | disclosed |
| JP-2001072680-A | NEW METHOD FOR PRODUCING PURINE IODIDE DERIVATIVE | EISAI CO LTD | 2001-03-21 | — | — | JP | disclosed |
| JP-2001072680-A | NEW METHOD FOR PRODUCING PURINE IODIDE DERIVATIVE | EISAI CO LTD | 2001-03-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12234243-B1 | Diorganyl diselenide-clubbed quaternary purines as corrosion inhibitors | AOC1, DCTD, UNG | ALDH1A1 924/4885KDM4E 677/4885PI4KA 4505/4885 |
| US-12221451-B1 | Diorganyl diselenide-clubbed quaternary purines as corrosion inhibitors | AOC1, DCTD, UNG | ALDH1A1 924/4885KDM4E 677/4885PI4KA 4505/4885 |
| US-20250074914-A1 | DIORGANYL DISELENIDE-CLUBBED QUATERNARY PURINES AS CORROSION INHIBITORS | AOC1, DCTD, UNG | ALDH1A1 924/4885KDM4E 677/4885PI4KA 4505/4885 |
| US-20250074915-A1 | DIORGANYL DISELENIDE-CLUBBED QUATERNARY PURINES AS CORROSION INHIBITORS | AOC1, DCTD, UNG | ALDH1A1 924/4885KDM4E 677/4885PI4KA 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.