Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903580 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MAPTTDP1L3MBTL1HTT | |
| SCHEMBL1143293 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTTDP1L3MBTL1HTT | |
| Hydrochloric Acid SCHEMBL1143292 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTTDP1L3MBTL1HTT | |
| SCHEMBL11793140 | 0.78 | CA1 (0.85) | ALDH1A1MAPTHTTCA1CA2 | |
| SCHEMBL540915 | 0.78 | CA1 (0.85) | ALDH1A1MAPTHTTCA1CA2 | |
| SCHEMBL7122971 | 0.76 | UCHL1 (0.76) | ALDH1A1MAPTL3MBTL1HTTCA1 | |
| SCHEMBL28317290 | 0.75 | CA1 (0.63) | ALDH1A1MAPTL3MBTL1HTTLMNA | |
| SCHEMBL1417537 | 0.74 | CA1 (0.71) | ALDH1A1MAPTTDP1HTTLMNA | |
| SCHEMBL2240008 | 0.74 | CA1 (0.71) | ALDH1A1MAPTTDP1HTTLMNA | |
| SCHEMBL27516685 | 0.74 | CA1 (0.71) | ALDH1A1MAPTHTTLMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | PPARG, PPARA, PPARD | ALDH1A1 583/4885MAPT 4391/4885TDP1 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.