Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922117 | 0.88 | ELANE (0.43) | PTGS2ABCB1AGTR1 | |
| SCHEMBL6919743 | 0.87 | AGTR1 (0.53) | PTGS2ABCB1AGTR1KDM4EMAPT | |
| SCHEMBL6919614 | 0.85 | PTGS2 (0.46) | PTGS2ABCB1AGTR1KDM4E | |
| SCHEMBL7128402 | 0.80 | PTGS2 (0.47) | PTGS2ABCB1AGTR1KDM4EMAPT | |
| SCHEMBL6471642 | 0.77 | POLB (0.44) | AGTR1KDM4EMAPT | |
| SCHEMBL6821037 | 0.77 | ABCB1 (0.43) | PTGS2ABCB1AGTR1KDM4E | |
| SCHEMBL6920234 | 0.76 | P2RX4 (0.45) | PTGS2ABCB1AGTR1MAPTPTGS1 | |
| SCHEMBL6918827 | 0.76 | HTR6 (0.44) | PTGS2KDM4EPTGS1 | |
| SCHEMBL3555919 | 0.76 | KDM4E (0.45) | KDM4EMAPT | |
| SCHEMBL6824409 | 0.73 | KDM4E (0.40) | PTGS2ABCB1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |