Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922115 | 0.88 | ELANE (0.44) | PTGS2ABCB1AGTR1CYP1A2LMNA | |
| SCHEMBL6919741 | 0.87 | AGTR1 (0.55) | PTGS2ABCB1AGTR1KDM4EMAPT | |
| SCHEMBL7128404 | 0.80 | PTGS2 (0.46) | PTGS2ABCB1AGTR1KDM4EMAPT | |
| SCHEMBL6919614 | 0.78 | PTGS2 (0.46) | PTGS2ABCB1AGTR1KDM4EALDH1A1 | |
| SCHEMBL6471641 | 0.75 | POLB (0.45) | AGTR1KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL6920229 | 0.75 | P2RX4 (0.47) | PTGS2ABCB1AGTR1MAPTPTGS1 | |
| SCHEMBL6918823 | 0.75 | AKR1C3 (0.43) | PTGS2KDM4EPTGS1ALDH1A1AKR1C4 | |
| SCHEMBL6920262 | 0.74 | AGTR1 (0.39) | PTGS2ABCB1AGTR1KDM4EMAPT | |
| SCHEMBL6821037 | 0.70 | ABCB1 (0.43) | PTGS2ABCB1AGTR1KDM4EALDH1A1 | |
| SCHEMBL6922120 | 0.69 | MAPT (0.42) | KDM4EMAPTCYP1A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |