SCHEMBL7128422

SCHEMBL7128422

CCOc1cccc([SiH2]CCN)c1OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.41
▸ L3MBTL1 Q9Y468 4/20 0.36
▸ HTR2A P28223 2/20 0.35
▸ HTR2C P28335 2/20 0.35
▸ HTR2B P41595 2/20 0.35
▸ HTR1A P08908 1/20 0.34
▸ ADRA1D P25100 1/20 0.34
▸ ADRA1A P35348 1/20 0.34
▸ ADRA1B P35368 1/20 0.34
▸ MAPT P10636 3/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ PKM P14618 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ TSHR P16473 2/20 0.33
▸ PABPC1 P11940 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9176210 0.92 ALDH1A1 (0.40) ALDH1A1L3MBTL1HTR2AHTR2CHTR2B
SCHEMBL707161 0.90 ALDH1A1 (0.41) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A
SCHEMBL9165721 0.89 ALDH1A1 (0.38) ALDH1A1L3MBTL1HTR2AHTR2CHTR2B
SCHEMBL7806968 0.87 ALDH1A1 (0.39) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A
SCHEMBL647737 0.87 ALDH1A1 (0.39) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A
SCHEMBL707985 0.87 ALDH1A1 (0.39) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A
SCHEMBL21066803 0.84 ALDH1A1 (0.37) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A
SCHEMBL646941 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A
SCHEMBL28754933 0.83 ALDH1A1 (0.41) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A
SCHEMBL11350174 0.83 L3MBTL1 (0.37) ALDH1A1L3MBTL1HTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 — — EP claimed
US-6664021-B1 Acid generator and silicon-containing polyimide ester precursor comprising partially esterified silicon-containing polyamic ester; radiating with light CHISSO CORPORATION (JP) 2003-12-16 — — US disclosed
EP-0456469-B1 Photosensitive heat-resistant polymer having hydroxyphenyl group CHISSO CORP (JP) 1996-08-21 — — EP disclosed
US-5473040-A A protective coatings comprising a crosslinked terpolymer of polyimide, polysilsesquioxane and polysiloxane; hardness, heat resistance, insulation CHISSO CORPORATION (JP) 1995-12-05 — — US disclosed
US-5449588-A Shrinkage inhibition CHISSO CORPORATION (JP) 1995-09-12 — — US disclosed
US-5342739-A Coating a substrate with a polyamic acid modified by an amino- or hydroxy-substituted phenol; shelf life CHISSO CORPORATION (JP) 1994-08-30 — — US disclosed
US-5320935-A Method of forming a pattern from a photosensitive heat-resistant poly(amide)imide having hydroxyphenyl groups CHISSO CORPORATION (JP) 1994-06-14 — — US disclosed
US-5298359-A Combined with initiator,, an azide, an unsaturated compound CHISSO CORPORATION (JP) 1994-03-29 — — US disclosed
EP-0456469-A2 Photosensitive heat-resistant polymer having hydroxyphenyl group Chisso Corporation (JP) 1991-11-13 — — EP disclosed
US-4963635-A REACTING A FLUORINE-CONTAINING DIANHYDRIDE OR DIANHYDRIDE, A FLUORINE-CONTAINING DIAMINE OR A DEIAMINE AND AN AMINO-CONTAINING OXYSILANE COMPOUND CHISSO CORPORATION (JP) 1990-10-16 — — US disclosed
Send feedback