SCHEMBL7129110

SCHEMBL7129110

CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc2c(c1)CN(CCOc1cccc(C#N)c1)C2=O

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.59
ALOX5AP P20292 17/20 0.43
FEN1 P39748 16/20 0.43
HRH3 Q9Y5N1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7118364 0.85 RAB9A (0.47) F10ALOX5APFEN1
SCHEMBL7121877 0.83 F10 (0.57) F10ALOX5APFEN1
SCHEMBL7121933 0.81 HPGD (0.44) F10ALOX5APFEN1
SCHEMBL7121923 0.79 F10 (0.81) F10ALOX5APFEN1
SCHEMBL7117836 0.75 ALOX5AP (0.51) F10ALOX5APFEN1
SCHEMBL7123485 0.74 F10 (1.00) F10
SCHEMBL7118369 0.73 RAB9A (0.41) HRH3
SCHEMBL7128783 0.73 ALOX5AP (0.47) F10ALOX5APFEN1
SCHEMBL7125640 0.72 LMNA (0.51) ALOX5APFEN1
SCHEMBL7130064 0.71 ALOX5AP (0.38) F10ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030114448-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2003-06-19 US disclosed
WO-2002096873-A1 ISOINDOLE AND ISOQUINOLINE DERIVATIVES AS INHIBITORS OF FACTOR XA MILLENNIUM PHARMACEUTICALS, INC. (US) 2002-12-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114448-A1 Inhibitors of factor Xa SERPINC1, F11, TFPI F10 7/4885ALOX5AP 415/4885FEN1 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.