Sugi Predict

Sugi Predict / Compounds / SCHEMBL7129320

SCHEMBL7129320

SCHEMBL7129320

CN1c2ccccc2Sc2cc(CCO)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.58
▸ NOX1 Q9Y5S8 8/20 0.56
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ HTR2C P28335 2/20 0.56
▸ HTR2B P41595 2/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ ADRA2A P08913 1/20 0.56
▸ ADRA2B P18089 1/20 0.56
▸ ADRA2C P18825 1/20 0.56
▸ CHRM3 P20309 1/20 0.56
▸ SLC6A2 P23975 1/20 0.56
▸ SLC6A4 P31645 1/20 0.56
▸ DRD3 P35462 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ MAPT P10636 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ POLB P06746 1/20 0.40
▸ PABPC1 P11940 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7125071 0.88 MAOA (0.61) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL13888145 0.83 MAOA (0.63) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL8711778 0.81 MAOA (0.61) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL25028032 0.79 MAOA (0.58) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL20760007 0.79 NOX1 (0.46) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL2307240 0.77 TDP1 (0.46) MAOANOX1HTR2CHTR2BMEN1
SCHEMBL29377505 0.76 MAOA (1.00) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL231247 0.76 MAOA (1.00) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL628786 0.76 MAOA (0.68) MAOANOX1L3MBTL1HTR2CHTR2B
SCHEMBL7170967 0.75 MAOA (0.73) MAOANOX1L3MBTL1HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 — — US claimed
JP-2000512267-A — — 2000-09-19 — — JP claimed
EP-0912097-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1999-05-06 — — EP claimed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 — — WO claimed
US-6660503-B2 In aqueous solution NOVOZYMES A/S (DK) 2003-12-09 — — US disclosed
EP-0935692-B1 FABRIC TREATED WITH CELLULASE AND OXIDOREDUCTASE NOVOZYMES AS (DK) 2002-11-27 — — EP disclosed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 — — US disclosed
EP-0912097-B1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVOZYMES AS (DK) 2002-08-07 — — EP disclosed
EP-0787230-B1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVOZYMES AS (DK) 2002-03-20 — — EP disclosed
US-6346401-B1 OXIDATION OF HYDROXY GROUP OF SUGAR MONOMER OF STARCH BY CONTACTING WITH PEROXIDASE, HYDROGEN PEROXIDE AND ENHANCING AGENT IN AQUEOUS MEDIUM; FORMS CARBONYL OR CARBOXYLATE GROUP NOVOZYMES A/S (DK) 2002-02-12 — — US disclosed
US-20010055794-A1 Modification of polysaccharides by means of a phenol oxidizing enzyme NOVOZYMES A/S (DK) 2001-12-27 — — US disclosed
EP-0946207-B1 A METHOD FOR ENZYMATIC TREATMENT OF BIOFILM NOVOZYMES AS (DK) 2001-10-24 — — EP disclosed
WO-1997043382-A1 DETERGENT COMPOSITION COMPRISING A LACCASE ENZYME AND A DYE TRANSFER INHIBITING POLYMER THE PROCTER & GAMBLE COMPANY (US) 1997-11-20 — — WO disclosed
WO-1997040229-A1 FABRIC TREATED WITH A CELLULASE AND A HYBRID ENZYME COMPRISING A PHENOL OXIDIZING ENZYME NOVO NORDISK A/S (DK) 1997-10-30 — — WO disclosed
WO-1997040127-A1 BLEACHING OF FABRIC WITH A HYBRID ENZYME CONTAINING A PHENOL OXIDIZING ENZYME FUSED TO A CELLULOSE BINDING DOMAIN NOVO NORDISK A/S (DK) 1997-10-30 — — WO disclosed
EP-0787230-A1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVO NORDISK A/S (DK) 1997-08-06 — — EP disclosed
WO-1997025469-A1 TEXTILES BLEACHING/BRIGHTENING NOVO NORDISK A/S (DK) 1997-07-17 — — WO disclosed
WO-1997025468-A1 FABRIC TREATED WITH CELLULASE AND OXIDOREDUCTASE NOVO NORDISK A/S (DK) 1997-07-17 — — WO disclosed
WO-1996012846-A1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVO NORDISK A/S (DK) 1996-05-02 — — WO disclosed
WO-1996006930-A1 COPRINACEAE LACCASES NOVO NORDISK A/S (DK) 1996-03-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 MAOA 1245/4885NOX1 261/4885L3MBTL1 1293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.