Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CASP6 | P55212 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 6/20 | 0.36 |
| ▸ | NSD2 | O96028 | 3/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100127 | 0.81 | CASP6 (0.41) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL30052645 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL1755228 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL9646090 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL7130924 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL8508622 | 0.78 | TIMP3 (0.47) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL313371 | 0.76 | TTR (0.53) | ALDH1A1HSD17B10MPLNSD2DUSP3 | |
| SCHEMBL1809359 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL3899723 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL3826191 | 0.73 | ALDH1A1 (0.47) | ALDH1A1CASP6HSD17B10CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776947-B1 | Fiber-reactive dyestuffs, their preparation and use | CIBA SC HOLDING AG (CH) | 2000-04-26 | — | — | EP | claimed |
| US-5837827-A | Fibre-reactive dyes, their preparation and their use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-11-17 | — | — | US | claimed |
| EP-0776947-A1 | Fiber-reactive dyestuffs, their preparation and use | Ciba SC Holding AG (CH) | 1997-06-04 | — | — | EP | claimed |
| US-6670457-B2 | Use for dyeing or printing textile fibre materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-12-30 | — | — | US | disclosed |
| US-20030055230-A1 | Reactive dyes, their preparation and use | HUNTSMAN INTERNATIONAL LLC | 2003-03-20 | — | — | US | disclosed |
| EP-0739950-B1 | Reactive dioxazine dye stuffs, their preparation and use | CIBA SC HOLDING AG (CH) | 2002-09-18 | — | — | EP | disclosed |
| EP-0764694-B1 | Reactive dyes, their preparation and use thereof | CIBA SC HOLDING AG (CH) | 2001-11-07 | — | — | EP | disclosed |
| EP-0785237-B1 | Reactive dyes, their preparation and use | CIBA SC HOLDING AG (CH) | 2001-07-11 | — | — | EP | disclosed |
| EP-0776947-B1 | Fiber-reactive dyestuffs, their preparation and use | CIBA SC HOLDING AG (CH) | 2000-04-26 | — | — | EP | disclosed |
| EP-0763570-B1 | Reactive dyes, their preparation and use thereof | CIBA SC HOLDING AG (CH) | 2000-03-29 | — | — | EP | disclosed |
| US-5969113-A | DYE COTTON OR WOOL IN BRILLIANT COLORS WITH GOOD LIGHTFASTNESS AND WASHFASTNESS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5837827-A | Fibre-reactive dyes, their preparation and their use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |
| US-5817779-A | Azo reactive dyes, their preparation and use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5712376-A | Azo reactive dyes, their preparation and use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0785237-A1 | Reactive dyes, their preparation and use | Ciba SC Holding AG (CH) | 1997-07-23 | — | — | EP | disclosed |
| EP-0776947-A1 | Fiber-reactive dyestuffs, their preparation and use | Ciba SC Holding AG (CH) | 1997-06-04 | — | — | EP | disclosed |
| EP-0763570-A1 | Reactive dyes, their preparation and use thereof | Ciba SC Holding AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| EP-0739950-A2 | Reactive dioxazine dye stuffs, their preparation and use | CIBA-GEIGY AG (CH) | 1996-10-30 | — | — | EP | disclosed |