Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CASP6 | P55212 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901952 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL3817948 | 0.82 | ALDH1A1 (0.54) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL3819438 | 0.82 | ALDH1A1 (0.54) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL3818496 | 0.82 | ALDH1A1 (0.54) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL10508205 | 0.81 | NT5E (0.54) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL1755142 | 0.79 | HSD17B10 (0.65) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL7129368 | 0.78 | ALDH1A1 (0.39) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL157168 | 0.77 | CASP6 (0.55) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL11518386 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL29574227 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CASP6CYP2C9HSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776947-B1 | Fiber-reactive dyestuffs, their preparation and use | CIBA SC HOLDING AG (CH) | 2000-04-26 | — | — | EP | claimed |
| US-5837827-A | Fibre-reactive dyes, their preparation and their use | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-11-17 | — | — | US | claimed |
| EP-0776947-A1 | Fiber-reactive dyestuffs, their preparation and use | Ciba SC Holding AG (CH) | 1997-06-04 | — | — | EP | claimed |
| US-6670457-B2 | Use for dyeing or printing textile fibre materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-12-30 | — | — | US | disclosed |
| US-20030055230-A1 | Reactive dyes, their preparation and use | HUNTSMAN INTERNATIONAL LLC | 2003-03-20 | — | — | US | disclosed |
| CN-1097076-C | Active dye, their preparation and use | CIBA SPECIALTY CHEMICALS HOLSI (CH) | 2002-12-25 | — | — | CN | disclosed |
| EP-0739950-B1 | Reactive dioxazine dye stuffs, their preparation and use | CIBA SC HOLDING AG (CH) | 2002-09-18 | — | — | EP | disclosed |
| EP-0764694-B1 | Reactive dyes, their preparation and use thereof | CIBA SC HOLDING AG (CH) | 2001-11-07 | — | — | EP | disclosed |
| EP-0728818-B1 | Mixtures of azo dyes and their use | CIBA SC HOLDING AG (CH) | 2001-07-25 | — | — | EP | disclosed |
| EP-0785237-B1 | Reactive dyes, their preparation and use | CIBA SC HOLDING AG (CH) | 2001-07-11 | — | — | EP | disclosed |
| CN-1058012-C | Reactive dyes from dioxazine series, their preparation and use | CIBA SC HOLDING AG (CH) | 2000-11-01 | — | — | CN | disclosed |
| EP-0785237-A1 | Reactive dyes, their preparation and use | Ciba SC Holding AG (CH) | 1997-07-23 | — | — | EP | disclosed |
| EP-0776947-A1 | Fiber-reactive dyestuffs, their preparation and use | Ciba SC Holding AG (CH) | 1997-06-04 | — | — | EP | disclosed |
| EP-0764694-A1 | Reactive dyes, their preparation and use thereof | Ciba SC Holding AG (CH) | 1997-03-26 | — | — | EP | disclosed |
| EP-0763570-A1 | Reactive dyes, their preparation and use thereof | Ciba SC Holding AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| CN-1142500-A | Reactive dyes from dioxazine series, their preparation and use | CIBA GEIGY AG (CH) | 1997-02-12 | — | — | CN | disclosed |
| EP-0739950-A2 | Reactive dioxazine dye stuffs, their preparation and use | CIBA-GEIGY AG (CH) | 1996-10-30 | — | — | EP | disclosed |
| US-5565553-A | CELLULOSIC OR COTTON FIBER-REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0728818-A1 | Mixtures of azo dyes and their use | CIBA-GEIGY AG (CH) | 1996-08-28 | — | — | EP | disclosed |
| EP-0647683-A1 | Reactive dyestuffs, process for their production and their use | CIBA-GEIGY AG (CH) | 1995-04-12 | — | — | EP | disclosed |