Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5874143 | 0.85 | OPRM1 (0.61) | HTTKMT2ASMN1; SMN2OPRM1LMNA | |
| SCHEMBL28148420 | 0.81 | MTNR1A (0.44) | SMN1; SMN2NFKB1ALDH1A1ALOX15HDAC7 | |
| SCHEMBL7688624 | 0.80 | GAA (0.53) | HTTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL5253490 | 0.76 | HTT (0.59) | HTTKMT2AMEN1DDB1CRBN | |
| Hydrochloric Acid SCHEMBL5186439 | 0.75 | HTT (0.58) | HTTKMT2AMEN1DDB1CRBN | |
| SCHEMBL10920889 | 0.74 | DRD1 (0.35) | KMT2AMEN1NFKB1LMNAALDH1A1 | |
| SCHEMBL14663483 | 0.72 | ALDH1A1 (0.62) | HTTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL5573918 | 0.71 | HDAC4 (0.35) | OPRM1HDAC7TSHRNPSR1 | |
| SCHEMBL28381732 | 0.71 | PDPK1 (0.44) | KMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL10923547 | 0.71 | CYP2D6 (0.38) | KMT2AMEN1NFKB1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003231635-A | MEDICINAL COMPOSITION | TANABE SEIYAKU CO LTD | 2003-08-19 | — | — | JP | disclosed |
| JP-2002121192-A | BENZOYLAMINOISOINDOLINE DERIVATIVE, METHOD OF PRODUCING THE SAME AND INTERMEDIATE THEREFOR | TANABE SEIYAKU CO LTD | 2002-04-23 | — | — | JP | disclosed |
| WO-2002014276-A1 | BENZOYLAMINOISOINDOLINE COMPOUNDS, PROCESSES FOR THE PREPARATION OF THE SAME AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 2002-02-21 | — | — | WO | disclosed |