Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129435 | 0.80 | HTT (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6615213 | 0.75 | TAS1R3 (0.62) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28148420 | 0.74 | MTNR1A (0.44) | ALDH1A1SMN1; SMN2NPSR1TSHRTP53 | |
| SCHEMBL3730600 | 0.73 | GAA (0.52) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6711198 | 0.70 | GAA (0.76) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28138333 | 0.69 | TAS1R3 (0.56) | GAAALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL8889128 | 0.69 | GAA (0.55) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7232761 | 0.69 | GAA (0.74) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10920889 | 0.68 | DRD1 (0.35) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5068216 | 0.67 | GAA (0.59) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014277-A1 | BIPHENYLCARBOXAMIDOISOINDOLINE COMPOUNDS, PROCESSES FOR THE PREPARATION OF THE SAME AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 2002-02-21 | — | — | WO | disclosed |