SCHEMBL7129477

SCHEMBL7129477

CC1=Nc2ncc(S(=O)(=O)O)cc2C1(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24934068 0.83 KDM4E (0.36) KDM4ERXRARXRBRXRG
SCHEMBL47326 0.74 RXRA (0.37) KDM4ERXRARXRBRXRG
SCHEMBL29869219 0.74 RXRA (0.37) KDM4ERXRARXRBRXRG
SCHEMBL2721236 0.73 RXRA (0.36) KDM4ERXRARXRBRXRG
SCHEMBL224968 0.73 RXRA (0.36) KDM4ERXRARXRBRXRG
Potassium SCHEMBL559580 0.73 RXRA (0.36) KDM4ERXRARXRBRXRG
SCHEMBL23961228 0.73 RXRA (0.33) RXRARXRBRXRG
SCHEMBL137432 0.72 RXRA (0.30) RXRARXRBRXRG
SCHEMBL10265050 0.71 HRH4 (0.31)
SCHEMBL1714555 0.71 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2003064083-A 2,3,3-TRIMETHYL-3H-PYRROLO[2,3-b]PYRIDINE-5-SULFONIC ACID AND DERIVATIVE THEREOF FUJI PHOTO FILM CO LTD 2003-03-05 JP disclosed