SCHEMBL224968

SCHEMBL224968

CC1=Nc2ccc(S(=O)(=O)O)cc2C1(C)C.[KH]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
SNCA P37840 1/20 0.36
ALDH1A1 P00352 10/20 0.35
HSD17B10 Q99714 4/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA12 O43570 2/20 0.35
CA7 P43166 2/20 0.35
CA14 Q9ULX7 2/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 5/20 0.34
LMNA P02545 3/20 0.34
GAA P10253 1/20 0.34
HTT P42858 2/20 0.33
CASP6 P55212 2/20 0.33
KDM4E B2RXH2 4/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29869219 0.98 RXRA (0.37) RXRARXRBRXRGSNCAALDH1A1
SCHEMBL47326 0.98 RXRA (0.37) RXRARXRBRXRGSNCAALDH1A1
Potassium SCHEMBL559580 0.97 RXRA (0.36) RXRARXRBRXRGSNCAALDH1A1
SCHEMBL2721236 0.97 RXRA (0.36) RXRARXRBRXRGSNCAALDH1A1
SCHEMBL11852597 0.85 G6PD (0.38) RXRAKMT2AMEN1LMNAPTGS1
SCHEMBL2721232 0.84 LMNA (0.44) KMT2AMEN1LMNATDP1
Potassium Ion SCHEMBL224967 0.84 LMNA (0.41) KMT2AMEN1LMNATDP1
SCHEMBL6027095 0.84 MAPT (0.42) CA1CA2CA12CA7CA14
SCHEMBL13962645 0.84 ALDH1A1 (0.34) ALDH1A1HSD17B10KMT2AMEN1TDP1
Potassium Ion SCHEMBL29727670 0.84 LMNA (0.41) KMT2AMEN1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113337138-B Indole cyanine dye 天津全和诚科技有限责任公司 2022-08-09 CN claimed
CN-113462186-A sulfo-Cy 3 carboxylic acid fluorescent dye and preparation process thereof 江西高信前沿科技有限公司 2021-10-01 CN claimed
CN-113337138-A Novel indole cyanine dye 天津全和诚科技有限责任公司 2021-09-03 CN claimed
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2026-04-30 US disclosed
US-20250275943-A1 COMPOSITION FOR CANCER DIAGNOSIS TARGETING TUMOR AND/OR TUMOR MICROENVIRONMENT AND USE THEREOF The General Hospital Cooperation d/b/a Massachusetts General Hospital (MGH) 2025-09-04 US disclosed
WO-2025095666-A1 NOVEL OXOCYANINE-BASED COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 포항공과대학교 산학협력단 2025-05-08 WO disclosed
EP-4529551-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2025-04-02 EP disclosed
WO-2023227601-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2023-11-30 WO disclosed
US-20220387632-A1 RENAL CLEARABLE FLUORESCENT CONTRAST AGENT WITH INCREASED TUMOR SPECIFICITY, AND IMAGING METHOD USING SAME NAWOOVISION CO., LTD. (KP) 2022-12-08 US disclosed
CN-113337138-B Indole cyanine dye 天津全和诚科技有限责任公司 2022-08-09 CN disclosed
CN-113462186-A sulfo-Cy 3 carboxylic acid fluorescent dye and preparation process thereof 江西高信前沿科技有限公司 2021-10-01 CN disclosed
US-20030224391-A1 Rigidized trimethine cyanine dyes CARNEGIE MELLON UNIVERSITY 2003-12-04 US disclosed
EP-1078023-A4 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 2003-03-26 EP disclosed
US-6538129-B1 Luminescent compounds Terpetschnig, Ewald A. 2003-03-25 US disclosed
EP-1042407-B1 RIGIDIZED TRIMETHINE CYANINE DYES UNIV CARNEGIE MELLON (US) 2001-09-12 EP disclosed
EP-0898596-B1 SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD AMERSHAM PHARM BIOTECH UK LTD (GB) 2001-08-29 EP disclosed
EP-1078023-A1 LUMINESCENT COMPOUNDS Terpetschnig, Ewald A. (US) 2001-02-28 EP disclosed
US-6140494-A INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) 2000-10-31 US disclosed
US-6133445-A USEFUL FOR IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS CARNEGIE MELLON UNIVERSITY (US) 2000-10-17 US disclosed
WO-1999051702-A1 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 1999-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES CBR1, CBR3, NR2E3 RXRA 322/4885RXRB 179/4885RXRG 334/4885
US-20220387632-A1 RENAL CLEARABLE FLUORESCENT CONTRAST AGENT WITH INCREASED TUMOR SPECIFICITY, AND IMAGING METHOD USING SAME RCC2, REN, VHL RXRA 2422/4885RXRB 2739/4885RXRG 2346/4885
US-20030224391-A1 Rigidized trimethine cyanine dyes CBR1, TH, CBR3 RXRA 653/4885RXRB 356/4885RXRG 1164/4885
US-20250275943-A1 COMPOSITION FOR CANCER DIAGNOSIS TARGETING TUMOR AND/OR TUMOR MICROENVIRONMENT AND USE THEREOF FOLR1, FOLR2, MSR1 RXRA 410/4885RXRB 319/4885RXRG 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.