Potassium

Potassium

SCHEMBL559580

CC1=Nc2ccc(S(=O)(=O)O)cc2C1(C)C.[K]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
SNCA P37840 1/20 0.36
ALDH1A1 P00352 10/20 0.35
HSD17B10 Q99714 4/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA12 O43570 2/20 0.35
CA7 P43166 2/20 0.35
CA14 Q9ULX7 2/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 5/20 0.34
LMNA P02545 3/20 0.34
GAA P10253 1/20 0.34
HTT P42858 2/20 0.33
CASP6 P55212 2/20 0.33
KDM4E B2RXH2 4/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47326 0.98 RXRA (0.37) RXRARXRBRXRGSNCAALDH1A1
SCHEMBL29869219 0.98 RXRA (0.37) RXRARXRBRXRGSNCAALDH1A1
SCHEMBL224968 0.97 RXRA (0.36) RXRARXRBRXRGSNCAALDH1A1
SCHEMBL2721236 0.97 RXRA (0.36) RXRARXRBRXRGSNCAALDH1A1
SCHEMBL11852597 0.85 G6PD (0.38) RXRAKMT2AMEN1LMNAPTGS1
Potassium Ion SCHEMBL224967 0.84 LMNA (0.41) KMT2AMEN1LMNATDP1
Potassium Ion SCHEMBL29727670 0.84 LMNA (0.41) KMT2AMEN1LMNATDP1
SCHEMBL6027095 0.84 MAPT (0.42) CA1CA2CA12CA7CA14
SCHEMBL2721232 0.84 LMNA (0.44) KMT2AMEN1LMNATDP1
SCHEMBL13962645 0.84 ALDH1A1 (0.34) ALDH1A1HSD17B10KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113337138-B Indole cyanine dye 天津全和诚科技有限责任公司 2022-08-09 CN claimed
CN-113337138-A Novel indole cyanine dye 天津全和诚科技有限责任公司 2021-09-03 CN claimed
CN-104804463-B Near-infrared fluorescent stain and preparation method and application for target tumor tissue 西安交通大学第附属医院 2016-08-24 CN claimed
CN-104804463-A Near-infrared fluorescence dye for targeting tumor tissue as well as preparation method and application XI AN MEIJIAJIA MEDICAL TECHNOLOGY CO LTD 2015-07-29 CN claimed
CN-113337138-B Indole cyanine dye 天津全和诚科技有限责任公司 2022-08-09 CN disclosed
CN-113337138-A Novel indole cyanine dye 天津全和诚科技有限责任公司 2021-09-03 CN disclosed
CN-104804463-B Near-infrared fluorescent stain and preparation method and application for target tumor tissue 西安交通大学第附属医院 2016-08-24 CN disclosed
US-9110069-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2015-08-18 US disclosed
CN-104804463-A Near-infrared fluorescence dye for targeting tumor tissue as well as preparation method and application XI AN MEIJIAJIA MEDICAL TECHNOLOGY CO LTD 2015-07-29 CN disclosed
EP-2129788-B1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS LLC (US) 2014-09-03 EP disclosed
US-20140086844-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC (US) 2014-03-27 US disclosed
US-8642014-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2014-02-04 US disclosed
US-20040166515-A1 Luminescent compounds TERPETSCHNIG, EWALD A. 2004-08-26 US disclosed
US-20030235846-A1 Luminescent compounds TERPTETSCHNIG, EWALD A. 2003-12-25 US disclosed
EP-1078023-A4 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 2003-03-26 EP disclosed
US-6538129-B1 Luminescent compounds Terpetschnig, Ewald A. 2003-03-25 US disclosed
US-6448008-B1 IMMUNOLOGICAL BINDING REAGENT LABELLED WITH A FLUORESCENT COMPOUND AND METHOD OF ASSAYING AN ANALYTE IN A SAMPLE COMPRISING CONTACTING A NUCLEIC ACID PROBE OR AN IMMUNOLOGICALLY BINDING REAGENT LABELLED WITH A FLUORESCENT INNOSENSE, S.R.L. (IT) 2002-09-10 US disclosed
EP-1078023-A1 LUMINESCENT COMPOUNDS Terpetschnig, Ewald A. (US) 2001-02-28 EP disclosed
EP-1065250-A1 New fluorescent cyanine labels containing a sulfamido linker arm Innosense S.r.l. (IT) 2001-01-03 EP disclosed
WO-1999051702-A1 LUMINESCENT COMPOUNDS TERPETSCHNIG EWALD A (US) 1999-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140086844-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS RXRA 4546/4885RXRB 4432/4885RXRG 4665/4885
US-20030235846-A1 Luminescent compounds CROCC, NR2E1, NDC1 RXRA 112/4885RXRB 134/4885RXRG 192/4885
US-20040166515-A1 Luminescent compounds RORC, NR2E3, RORB RXRA 43/4885RXRB 39/4885RXRG 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.