Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28769510 | 0.86 | SGMS2 (0.56) | SGMS2ALDH1A1KDM4EHTR1AADRA1D | |
| SCHEMBL791853 | 0.83 | HTR1A (0.74) | ALDH1A1KDM4EHTR1AADRA1DADRA1A | |
| SCHEMBL30416387 | 0.83 | HTR1A (0.74) | ALDH1A1KDM4EHTR1AADRA1DADRA1A | |
| SCHEMBL683595 | 0.81 | L3MBTL1 (0.58) | SGMS2ALDH1A1KDM4EHTR1AADRA1D | |
| Ammonia Solution, Strong SCHEMBL2063054 | 0.81 | HTR1A (0.72) | ALDH1A1KDM4EHTR1AADRA1DADRA1A | |
| SCHEMBL11603988 | 0.79 | MAPT (0.55) | SGMS2ALDH1A1KDM4EHTR1AADRA1D | |
| SCHEMBL27904061 | 0.79 | ABCB1 (0.50) | SGMS2ALDH1A1KDM4EHTR1AADRA1D | |
| SCHEMBL23046945 | 0.79 | MAPT (0.55) | SGMS2ALDH1A1KDM4EHTR1AADRA1D | |
| SCHEMBL9460741 | 0.79 | MAPT (0.55) | SGMS2ALDH1A1KDM4EHTR1AADRA1D | |
| SCHEMBL3458384 | 0.79 | TDP1 (0.55) | SGMS2ALDH1A1KDM4EHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020183540-A1 | Substituted tetraarylethylene compounds | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA | 2002-12-05 | — | — | US | claimed |
| US-6670512-B2 | Molecular templates for metal complexation | STRYKER JEFFREY MARK (CA) | 2003-12-30 | — | — | US | disclosed |
| US-20020183540-A1 | Substituted tetraarylethylene compounds | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183540-A1 | Substituted tetraarylethylene compounds | ABL1, ETV6, ALK | SGMS2 2881/4885ALDH1A1 1684/4885KDM4E 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.