Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL27774094 | 0.95 | TDP1 (0.53) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| SCHEMBL27753371 | 0.90 | GLRA1 (0.49) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| SCHEMBL18430835 | 0.86 | NISCH (0.55) | L3MBTL1MAPTMAPK1TDP1SGMS2 | |
| SCHEMBL10094328 | 0.86 | MAPT (0.51) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| SCHEMBL23046945 | 0.85 | MAPT (0.55) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| SCHEMBL9460741 | 0.85 | MAPT (0.55) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| SCHEMBL3458384 | 0.85 | TDP1 (0.55) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| SCHEMBL25146420 | 0.85 | MAPK1 (0.53) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| SCHEMBL24449689 | 0.84 | MAPT (0.54) | L3MBTL1MAPTMAPK1TDP1LIPE | |
| Hydrochloric Acid SCHEMBL9460764 | 0.84 | MAPT (0.53) | L3MBTL1MAPTMAPK1TDP1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221784-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | UNIVERSITÉ DE STRASBOURG (FR) | 2021-07-22 | — | — | US | disclosed |
| US-10206931-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | WUXI APPTEC (SHANGHAI) CO. LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | WUXI APPTEC (SHANGHAI) CO. LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | THE UNITED STATES OF AMERICA AS REPRESENTED BY SECRETARY DEPT OF HEALTH AND HUMAN SERVICE (US) | 2017-05-25 | — | — | US | disclosed |
| US-9452973-B2 | Modulators of the relaxin receptor 1 | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-09-27 | — | — | US | disclosed |
| US-9133186-B2 | Hetero ring-fused imidazole derivative having AMPK activating effect | SHIONOGI & CO., LTD. (JP) | 2015-09-15 | — | — | US | disclosed |
| US-9115122-B2 | Non-ATP dependent inhibitors of extracellular signal-regulated kinase (ERK) | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150216168-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20130184240-A1 | HETERO RING-FUSED IMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT | SHIONOGI & CO., LTD. (JP) | 2013-07-18 | — | — | US | disclosed |
| WO-2013016531-A2 | COMPOUNDS AND METHODS FOR USE IN TREATING NEOPLASIA AND CANCER | PURDUE RESEARCH FOUNDATION (US) | 2013-01-31 | — | — | WO | disclosed |
| US-8268803-B2 | 5, 6-ring annulated indole derivatives and use thereof | MERCK SHARP & DOHME CORP. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20100322901-A1 | 5, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF | SCHERING CORPORATION | 2010-12-23 | — | — | US | disclosed |
| EP-1718605-B1 | PROCESSES FOR THE PREPARATION OF ARYL-AND HETEROARYL-ALKYLSULFONYL HALIDES | WYETH CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20070066652-A1 | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066652-A1 | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | US | disclosed |
| EP-0486745-A1 | Improved solvents for chromogens useful in the manufacture of carbonless copying paper | MONSANTO EUROPE S.A./N.V. (BE) | 1992-05-27 | — | — | EP | disclosed |
| US-3968320-A | Dye solvents for pressure-sensitive record material | MONSANTO COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221784-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | ACHE, TRPV1, OPRL1 | L3MBTL1 4614/4885MAPT 572/4885MAPK1 2946/4885 |
| US-20130184240-A1 | HETERO RING-FUSED IMIDAZOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT | PRKAA1, PRKAA2, PRKAG1 | L3MBTL1 2717/4885MAPT 3580/4885MAPK1 360/4885 |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | L3MBTL1 4624/4885MAPT 1368/4885MAPK1 470/4885 |
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | EP300, CREBBP, HDAC1 | L3MBTL1 2291/4885MAPT 2745/4885MAPK1 579/4885 |
| US-20070066652-A1 | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | OPRM1, OPRD1, OPRL1 | L3MBTL1 2271/4885MAPT 4006/4885MAPK1 2503/4885 |
| US-10206931-B2 | Therapeutic compounds and uses thereof | EP300, CREBBP, HDAC1 | L3MBTL1 2291/4885MAPT 2745/4885MAPK1 579/4885 |
| US-20100322901-A1 | 5, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF | IDO1, IDO2, TPH1 | L3MBTL1 1796/4885MAPT 1314/4885MAPK1 4217/4885 |
| US-20150216168-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | ABAT, AAK1, AGXT | L3MBTL1 2857/4885MAPT 2879/4885MAPK1 957/4885 |
| US-20170144984-A1 | MODULATORS OF THE RELAXIN RECEPTOR 1 | RXFP1, RXFP2, RXFP3 | L3MBTL1 3143/4885MAPT 4541/4885MAPK1 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.