Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.73 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371901 | 0.93 | HDAC8 (0.83) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL16118213 | 0.89 | LMNA (0.61) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL27975953 | 0.87 | LMNA (0.63) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL26360091 | 0.85 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4310606 | 0.85 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL4315463 | 0.85 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL14675977 | 0.85 | HDAC3 (0.66) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9170867 | 0.85 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9115650 | 0.84 | HDAC3 (0.78) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9363122 | 0.83 | ALDH1A1 (0.57) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030097002-A1 | Enantioselective reactions using two-component chiral phase transfer catalysts in multiphasic systems | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2003-05-22 | — | — | US | disclosed |
| WO-2002092562-A2 | ENANTIOSELECTIVE REACTIONS USING TWO-COMPONENT CHIRAL PHASE TRANSFER CATALYSTS IN MULTIPHASIC SYSTEMS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097002-A1 | Enantioselective reactions using two-component chiral phase transfer catalysts in multiphasic systems | COASY, MOGAT2, ICMT | HDAC3 2313/4885HDAC1 3284/4885HDAC2 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.