Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129580 | 1.00 | LMNA (0.46) | LMNAALDH1A1KMT2AL3MBTL1MCOLN3 | |
| SCHEMBL7129578 | 1.00 | LMNA (0.46) | LMNAALDH1A1KMT2AL3MBTL1MCOLN3 | |
| SCHEMBL7115725 | 0.87 | MAPT (0.46) | LMNAALDH1A1KMT2AL3MBTL1TSHR | |
| SCHEMBL7115722 | 0.87 | MAPT (0.46) | LMNAALDH1A1KMT2AL3MBTL1TSHR | |
| SCHEMBL7115720 | 0.87 | MAPT (0.46) | LMNAALDH1A1KMT2AL3MBTL1TSHR | |
| SCHEMBL7117840 | 0.86 | L3MBTL1 (0.54) | ALDH1A1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL7117845 | 0.86 | L3MBTL1 (0.54) | ALDH1A1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL7117834 | 0.86 | L3MBTL1 (0.54) | ALDH1A1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL7130381 | 0.84 | HSD11B1 (0.51) | LMNAALDH1A1KMT2ANPSR1GAA | |
| SCHEMBL7130375 | 0.84 | HSD11B1 (0.51) | LMNAALDH1A1KMT2ANPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | LEXICON PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | QDPR, AZI2, NISCH | LMNA 4339/4885ALDH1A1 1333/4885KMT2A 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.