Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116603 | 0.77 | PRMT1 (0.43) | ALDH1A1POLBPRMT1OPRM1OPRD1 | |
| SCHEMBL7127023 | 0.76 | GHSR (0.42) | ALDH1A1NPSR1POLBKMT2APRMT1 | |
| SCHEMBL7118423 | 0.73 | LMNA (0.44) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7130241 | 0.70 | PLAU (0.54) | HTTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4278250 | 0.68 | L3MBTL1 (0.45) | ALDH1A1CYP2C19KMT2ATAAR1TSHR | |
| SCHEMBL5449745 | 0.67 | PRMT1 (0.68) | HTTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27915795 | 0.67 | PARP10 (0.54) | POLBKMT2APRMT1PLA2G10PLA2G2A | |
| SCHEMBL7124462 | 0.66 | GAA (0.45) | ALDH1A1CYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL7116706 | 0.65 | PLAU (0.59) | ALDH1A1CYP1A2CYP2C9CYP2C19PLAU | |
| SCHEMBL7127820 | 0.65 | GHSR (0.43) | ALDH1A1NPSR1KMT2APRMT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583318-B2 | Carrying out a four component condensation reaction between components consisting of a sulfonamide, an aldehyde or ketone, an isocyanide and a carboxylic acid, and one of such components being attached to a solid support | ADVANCED SYNTECH, LLC | 2003-06-24 | — | — | US | disclosed |
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ADVANCED SYNTECH LLC | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ASPH, COASY, HAAO | HTT 380/4885ALDH1A1 391/4885CYP1A2 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.