Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 7/20 | 0.60 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126449 | 0.77 | CYP24A1 (0.94) | CYP24A1CYP27B1 | |
| SCHEMBL1503388 | 0.74 | CYP24A1 (1.00) | CYP24A1CYP27B1 | |
| SCHEMBL1503385 | 0.74 | CYP24A1 (1.00) | CYP24A1CYP27B1 | |
| SCHEMBL8540395 | 0.74 | CYP24A1 (1.00) | CYP24A1CYP27B1 | |
| SCHEMBL17793731 | 0.72 | MAPT (0.64) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14863192 | 0.72 | CYP19A1 (0.54) | CYP24A1CYP27B1MAPTMEN1KMT2A | |
| SCHEMBL16700855 | 0.71 | CYP17A1 (0.68) | CYP24A1CYP3A4 | |
| SCHEMBL11214315 | 0.71 | CYP19A1 (0.61) | CYP24A1CYP27B1MAPTMEN1KMT2A | |
| SCHEMBL11366789 | 0.70 | CYP19A1 (1.00) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL8535942 | 0.68 | CYP19A1 (0.61) | CYP24A1CYP27B1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | claimed |