SCHEMBL7130431

SCHEMBL7130431

O=C(CCN1CCOCC1)C1CNCCO1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.40
KMT2A Q03164 6/20 0.39
ALDH1A1 P00352 4/20 0.39
MAPT P10636 4/20 0.39
MEN1 O00255 2/20 0.38
HSP90AA1 P07900 1/20 0.37
LMNA P02545 3/20 0.37
MPI P34949 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ATM Q13315 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3557649 0.77 GLA (0.44) GLASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL17559282 0.74 SSTR4 (0.42)
SCHEMBL8790846 0.74 SSTR4 (0.39)
SCHEMBL295209 0.74 SSTR4 (0.39)
SCHEMBL3459105 0.74 GLA (0.50) GLASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL10963648 0.74 SIGMAR1 (0.39)
SCHEMBL9113528 0.73 SSTR4 (0.38)
SCHEMBL15408885 0.73 SSTR4 (0.38) SMN1; SMN2KMT2AMEN1
SCHEMBL7310959 0.72 SSTR4 (0.42)
Morpholine SCHEMBL28052158 0.72 SSTR4 (0.40) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417644-B Preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2023-09-12 CN claimed
CN-108947937-B Co-production preparation method of acrylamide and formamide type compound 深圳有为技术控股集团有限公司 2023-05-16 CN claimed
CN-117946032-A Novel efficient preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2024-04-30 CN disclosed
CN-117777059-A Preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2024-03-29 CN disclosed
CN-117050037-A Preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2023-11-14 CN disclosed
CN-116925010-A Process for preparing acrylamide compound and its mixture by mixed anhydride method 深圳有为技术控股集团有限公司 2023-10-24 CN disclosed
CN-107417644-B Preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2023-09-12 CN disclosed
CN-108164477-B Process for preparing mono-or polyfunctional acrylamide compounds 深圳有为技术控股集团有限公司 2023-05-16 CN disclosed
CN-108947937-B Co-production preparation method of acrylamide and formamide type compound 深圳有为技术控股集团有限公司 2023-05-16 CN disclosed
CN-116075537-A Solvent for resin synthesis and method for producing synthetic resin using the same 科巨希化学股份有限公司 2023-05-05 CN disclosed
CN-115745826-A Co-production method and separation optimization of N, N-dimethylformamide and acrylamide type compound 深圳有为技术控股集团有限公司 2023-03-07 CN disclosed
CN-107973759-B Preparation method of acryloyl morpholine 湖南久日新材料有限公司 2021-03-05 CN disclosed
CN-110606834-A Preparation method of acryloyl morpholine 宁波南大光电材料有限公司 2019-12-24 CN disclosed
US-6506939-B1 Producing N-substituted acrylamides and tertiary amines CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2003-01-14 US disclosed
CN-1345302-A Method for producing acrylic acid monomer CIBA SPEC CHEM WATER TREAT LTD (GB) 2002-04-17 CN disclosed
EP-1140797-A1 PRODUCTION OF ACRYLIC MONOMERS Ciba Specialty Chemicals Water Treatments Limited (GB) 2001-10-10 EP disclosed
WO-2000041996-A1 PRODUCTION OF ACRYLIC MONOMERS CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2000-07-20 WO disclosed