SCHEMBL7130436

SCHEMBL7130436

CCCCCCCCCCCCCCCCCCN1CCN(S(=O)(=O)c2ccccc2)CC1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.59
PKM P14618 2/20 0.55
GAA P10253 1/20 0.55
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
DRD3 P35462 3/20 0.53
DRD2 P14416 2/20 0.53
HTR6 P50406 2/20 0.53
APOBEC3A P31941 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52
KCNH2 Q12809 1/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10724287 1.00 POLB (0.59) POLBPKMGAAKDM4ELMNA
SCHEMBL10721938 1.00 POLB (0.59) POLBPKMGAAKDM4ELMNA
SCHEMBL10728118 0.94 POLB (0.63) POLBPKMGAALMNADRD3
SCHEMBL10724375 0.88 POLB (0.67) POLBPKMGAADRD3DRD2
SCHEMBL2546084 0.85 POLB (0.55) POLBPKMMEN1KMT2A
SCHEMBL10726962 0.83 DRD2 (0.50) POLBPKMGAADRD3DRD2
SCHEMBL10723979 0.82 PKM (0.70) POLBPKMGAALMNAAPOBEC3A
SCHEMBL685172 0.81 POLB (0.67) POLBPKMGAALMNADRD3
SCHEMBL2561875 0.81 HTR1A (0.64) DRD3DRD2
SCHEMBL14313511 0.81 CHRNB2 (0.52) POLBPKMKDM4ELMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed