Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.79 |
| ▸ | NPC1 | O15118 | 6/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | MGLL | Q99685 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CDK9 | P50750 | 2/20 | 0.68 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713083 | 1.00 | RAB9A (0.79) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL17452451 | 0.89 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL31588094 | 0.87 | MEN1 (0.77) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL17452447 | 0.83 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL12217999 | 0.83 | MEN1 (0.72) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL19472583 | 0.83 | ASF1A (0.69) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL19472594 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL714435 | 0.80 | POLB (0.70) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL714433 | 0.80 | POLB (0.70) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 | |
| SCHEMBL12453329 | 0.80 | DUSP3 (0.76) | RAB9ASMN1; SMN2NPC1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730848-B2 | Protective molecules against anthrax toxin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-21 | — | — | US | disclosed |
| US-20120238604-A1 | CYTOTOXIC COMPOUNDS | MOLECULAR DISCOVERY SYSTEMS (AU) | 2012-09-20 | — | — | US | disclosed |
| CN-102625795-A | Cytotoxic compounds | MOLECULAR DISCOVERY SYSTEMS | 2012-08-01 | — | — | CN | disclosed |
| US-8124578-B2 | Use of dynamic mixtures for a controlled release of fragrances | FIRMENICH SA (CH) | 2012-02-28 | — | — | US | disclosed |
| WO-2011026193-A1 | CYTOTOXIC COMPOUNDS | MOLECULAR DISCOVERY SYSTEMS (AU) | 2011-03-10 | — | — | WO | disclosed |
| US-20070141011-A1 | USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES | UNIVERSITE LOUIS PASTEUR (FR) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | ANTXR2, TSG101, ANXA1 | RAB9A 1236/4885SMN1; SMN2 3581/4885NPC1 2411/4885 |
| US-20120238604-A1 | CYTOTOXIC COMPOUNDS | BAX, MKI67, EPCAM | RAB9A 857/4885SMN1; SMN2 185/4885NPC1 53/4885 |
| US-10730848-B2 | Protective molecules against anthrax toxin | ANTXR2, TSG101, ANXA1 | RAB9A 1236/4885SMN1; SMN2 3581/4885NPC1 2411/4885 |
| US-20070141011-A1 | USE OF DYNAMIC MIXTURES FOR A CONTROLLED RELEASE OF FRAGRANCES | TRPA1, HCN1, HCN4 | RAB9A 3745/4885SMN1; SMN2 3248/4885NPC1 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.