Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130860 | 0.78 | MAPT (0.49) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL29370463 | 0.75 | MAPT (0.57) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL11295618 | 0.75 | MAPT (0.68) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5952505 | 0.75 | MAPT (0.57) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL6525254 | 0.75 | MAPT (0.62) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9819647 | 0.74 | MAPT (0.56) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL7066317 | 0.74 | KMT2A (0.47) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL11406573 | 0.74 | KMT2A (0.59) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL8784838 | 0.74 | RAB9A (0.69) | KMT2AMEN1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL11659558 | 0.73 | MAPT (0.64) | KMT2AMEN1MAPTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |