Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003186 | 0.80 | KMT2A (0.53) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL11295618 | 0.79 | MAPT (0.68) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL11406573 | 0.78 | KMT2A (0.59) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL7130856 | 0.78 | KMT2A (0.53) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL11659558 | 0.77 | MAPT (0.64) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL11839764 | 0.77 | RAB9A (0.56) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL10494862 | 0.76 | ALDH1A1 (0.50) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL7045956 | 0.75 | KMT2A (0.53) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL11235710 | 0.75 | RAB9A (0.66) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL10494872 | 0.75 | KMT2A (0.48) | MAPTRAB9ASMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |