SCHEMBL7130874

SCHEMBL7130874

CC1=Cc2c(ccc(C)c2-c2ccccc2-c2ccccc2)C1C[SiH2]CC1C(C)=Cc2c1ccc(C)c2-c1ccccc1-c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609036 0.91 PDCD1 (0.33) PDCD1CD274
SCHEMBL4626569 0.89 KIF11 (0.30)
SCHEMBL1241178 0.85 PDCD1 (0.36) PDCD1CD274
SCHEMBL3997096 0.83 PDCD1 (0.35) PDCD1CD274
SCHEMBL21963541 0.81 PDCD1 (0.33) PDCD1CD274
SCHEMBL5609572 0.80 PDCD1 (0.35) PDCD1CD274
SCHEMBL4628528 0.77
SCHEMBL5610171 0.77 PDCD1 (0.31) PDCD1CD274
SCHEMBL6650592 0.76 PBRM1 (0.32)
SCHEMBL8405197 0.74 MAOA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1456217-A1 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2004-09-15 EP disclosed
WO-2003050131-A1 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-06-19 WO disclosed