Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713098 | 0.87 | HPGD (0.37) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL373198 | 0.84 | MAPT (0.35) | LMNAMAPTHPGDKDM4ERECQL | |
| SCHEMBL373548 | 0.84 | LMNA (0.36) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL373658 | 0.83 | MYC (0.37) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL7178326 | 0.81 | HPGD (0.41) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL373543 | 0.81 | HPGD (0.41) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL16693261 | 0.79 | L3MBTL1 (0.39) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL373648 | 0.79 | L3MBTL1 (0.39) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL373404 | 0.77 | PPARG (0.38) | LMNAMAPTHPGDKDM4ECYP3A4 | |
| SCHEMBL16693392 | 0.77 | SIRT5 (0.41) | LMNAMAPTHPGDKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822296-A1 | POLYMER MATERIAL | Menicon Co., Ltd. (JP) | 2021-05-19 | — | — | EP | disclosed |
| EP-3086162-B1 | OCULAR LENS | MENICON CO LTD (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-20180356561-A1 | GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER | JSR CORPORATION (JP) | 2018-12-13 | — | — | US | disclosed |
| EP-3086163-B1 | POLYSILOXANE-BASED MACROMONOMER FOR USE IN OCULAR LENS AND OCULAR LENS USING SAME | MENICON CO LTD (JP) | 2018-11-14 | — | — | EP | disclosed |
| EP-2857459-B1 | STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS | KOWA CO (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-9657131-B2 | Ophthalmic lens | MENICON CO., LTD. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9650473-B2 | Polysiloxane-based macromonomer for ophthalmic lens and ophthalmic lens using the same | MENICON CO., LTD. (JP) | 2017-05-16 | — | — | US | disclosed |
| EP-3086163-A1 | POLYSILOXANE-BASED MACROMONOMER FOR USE IN OCULAR LENS AND OCULAR LENS USING SAME | Menicon Co., Ltd. (JP) | 2016-10-26 | — | — | EP | disclosed |
| EP-3086162-A1 | OCULAR LENS | Menicon Co., Ltd. (JP) | 2016-10-26 | — | — | EP | disclosed |
| US-20160289368-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-0381005-B1 | Ocular lens material | MENICON CO LTD (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5346946-A | Polysiloxane macromonomer | MENICON CO., LTD (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0600269-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0584826-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584764-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5041511-A | Vinyl benzene acrylate or methacrylate crosslinking agent | MENICON CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| US-4954586-A | COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE | MENICON CO., LTD (JP) | 1990-09-04 | — | — | US | disclosed |
| EP-0381005-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1990-08-08 | — | — | EP | disclosed |
| EP-0379146-A2 | Soft ocular lens material | Menicon Co., Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |