SCHEMBL373548

SCHEMBL373548

C=C(C)C(=O)OCCN(CC)c1ccc(N=Nc2cc(C(=O)c3ccccc3)c(O)cc2O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.36
MAPT P10636 5/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP3A4 P08684 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
MEN1 O00255 2/20 0.35
MAOB P27338 2/20 0.34
HTT P42858 3/20 0.33
TP53 P04637 2/20 0.33
PPARG P37231 1/20 0.33
ALDH1A1 P00352 4/20 0.33
MAPK1 P28482 3/20 0.33
MYC P01106 1/20 0.33
ESRRG P62508 1/20 0.32
ELANE P08246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373242 0.88 HPGD (0.37) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL23406872 0.85 LMNA (0.35) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL373699 0.85 MEN1 (0.36) LMNAMAPTHPGDKDM4ERECQL
SCHEMBL373381 0.84 LMNA (0.36) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL16693261 0.83 L3MBTL1 (0.39) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL373648 0.83 L3MBTL1 (0.39) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL15357901 0.83 RAB9A (0.41) LMNAMAPTHPGDKDM4EHSD17B10
SCHEMBL373404 0.82 PPARG (0.38) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL373543 0.81 HPGD (0.41) LMNAMAPTHPGDKDM4ECYP3A4
SCHEMBL7178326 0.81 HPGD (0.41) LMNAMAPTHPGDKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023068316-A1 MATERIAL FOR SOFT CONTACT LENS HAVING CONTRAST IMPROVEMENT FUNCTION 興和株式会社 2023-04-27 WO disclosed
EP-3822296-A1 POLYMER MATERIAL Menicon Co., Ltd. (JP) 2021-05-19 EP disclosed
EP-3086162-B1 OCULAR LENS MENICON CO LTD (JP) 2019-04-17 EP disclosed
US-20180356561-A1 GEL, GEL MANUFACTURING METHOD, LENS, CONTACT LENS SURFACE MODIFIER, POLYMERIZABLE COMPOSITION, AND POLYMER JSR CORPORATION (JP) 2018-12-13 US disclosed
EP-3086163-B1 POLYSILOXANE-BASED MACROMONOMER FOR USE IN OCULAR LENS AND OCULAR LENS USING SAME MENICON CO LTD (JP) 2018-11-14 EP disclosed
EP-2857459-B1 STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS KOWA CO (JP) 2017-12-27 EP disclosed
US-9657131-B2 Ophthalmic lens MENICON CO., LTD. (JP) 2017-05-23 US disclosed
US-9650473-B2 Polysiloxane-based macromonomer for ophthalmic lens and ophthalmic lens using the same MENICON CO., LTD. (JP) 2017-05-16 US disclosed
EP-2330161-B1 DYE COMPOSITION FOR OPHTHALMIC LENS, METHOD FOR PRODUCING COLORED OPHTHALMIC LENS USING THE SAME AND COLORED OPHTHALMIC LENS MENICON CO LTD (JP) 2017-01-25 EP disclosed
EP-3086162-A1 OCULAR LENS Menicon Co., Ltd. (JP) 2016-10-26 EP disclosed
US-5416180-A Fluorine containing (meth)acrylate polymers MENICON CO., LTD. (JP) 1995-05-16 US disclosed
US-5416132-A Acrylamide modified acrylate modified polysiloxanes MENICON CO., LTD. (JP) 1995-05-16 US disclosed
EP-0381005-B1 Ocular lens material MENICON CO LTD (JP) 1995-01-11 EP disclosed
US-5346946-A Polysiloxane macromonomer MENICON CO., LTD (JP) 1994-09-13 US disclosed
EP-0600269-A2 Soft ocular lens material Menicon Co., Ltd. (JP) 1994-06-08 EP disclosed
EP-0584826-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0584764-A1 Ocular lens material Menicon Co., Ltd. (JP) 1994-03-02 EP disclosed
EP-0578087-A2 Ocular lens material Menicon Co., Ltd. (JP) 1994-01-12 EP disclosed
US-5041511-A Vinyl benzene acrylate or methacrylate crosslinking agent MENICON CO., LTD. (JP) 1991-08-20 US disclosed
US-4954586-A COPOLYMER OF A FLUORINE CONTAINING (METH)ACRYLATE, AN ALKYL (METH)ACRYLATE, A POLYSILOXANE AND A URETHANE CONTAINING POLYSILOXANE MENICON CO., LTD (JP) 1990-09-04 US disclosed