SCHEMBL7134010

SCHEMBL7134010

C=CCN(CC=C)CCc1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 10/20 1.00
HTR1A P08908 9/20 1.00
HTR6 P50406 9/20 1.00
HTR2C P28335 9/20 1.00
HTR2B P41595 8/20 1.00
ADRA2A P08913 7/20 1.00
ADRA2B P18089 7/20 1.00
ADRA2C P18825 7/20 1.00
HRH1 P35367 7/20 1.00
SLC6A4 P31645 7/20 1.00
HTR1D P28221 7/20 1.00
HTR1E P28566 6/20 1.00
DRD3 P35462 6/20 1.00
OPRK1 P41145 6/20 1.00
SLC6A3 Q01959 6/20 1.00
SIGMAR1 Q99720 6/20 1.00
ADRA1A P35348 6/20 1.00
SLC6A2 P23975 5/20 1.00
ADRA1B P35368 5/20 1.00
ALDH1A1 P00352 2/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31498037 0.92 HTR1A (0.84) HTR2AHTR1AHTR6HTR2CHTR2B
SCHEMBL24243748 0.92 HTR1A (0.84) HTR2AHTR1AHTR6HTR2CHTR2B
Hydrochloric Acid SCHEMBL30413582 0.90 HTR1A (0.82) HTR2AHTR1AHTR6HTR2CHTR2B
SCHEMBL24243770 0.90 HTR2A (0.82) HTR2AHTR1AHTR6HTR2CHTR2B
SCHEMBL31498058 0.90 HTR2A (0.82) HTR2AHTR1AHTR6HTR2CHTR2B
Hydrochloric Acid SCHEMBL30413017 0.89 HTR2A (0.80) HTR2AHTR1AHTR6HTR2CHTR2B
SCHEMBL18085051 0.89 HTR1A (0.80) HTR2AHTR1AHTR6HTR2CHTR2B
SCHEMBL18085058 0.87 HTR1A (0.76) HTR2AHTR1AHTR6HTR2CHTR2B
SCHEMBL23042907 0.85 HTR2A (0.74) HTR2AHTR1AHTR6HTR2CHTR2B
SCHEMBL30183299 0.85 HTR2A (0.74) HTR2AHTR1AHTR6HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness DRESDNER JR KARL P (US) 2026-04-02 US claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
EP-4247340-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS Bexson Biomedical, Inc. (US) 2023-09-27 EP claimed
US-11534454-B2 Complexing agent salt formulations of pharmaceutical compounds BEXSON BIOMEDICAL, INC. (US) 2022-12-27 US claimed
WO-2022109050-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL, INC. (US) 2022-05-27 WO claimed
US-20220160737-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2022-05-26 US claimed
US-20220152088-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL, INC. 2022-05-19 US claimed
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH TURTLE BEAR HOLDINGS LLC (US) 2026-04-23 US disclosed
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness DRESDNER JR KARL P (US) 2026-04-02 US disclosed
US-20260083759-A1 Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders HADASIT MED RES SERVICE (IL) 2026-03-26 US disclosed
EP-4704806-A1 INJECTABLE PHARMACEUTICAL FORMULATIONS Cybin IRL Limited (IE) 2026-03-11 EP disclosed
US-20260053831-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION DIAMOND THERAPEUTICS INC (CA) 2026-02-26 US disclosed
US-20200345585-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness DRESDNER JR KARL P (US) 2020-11-05 US disclosed
EP-3713568-A1 COMBINATION PRODUCT FOR THE TREATMENT OF NEUROLOGICAL AND/OR PSYCHIATRIC DISORDERS Consejo Superior de Investigaciones Cientificas (CSIC) (ES) 2020-09-30 EP disclosed
EP-0763032-B1 PALLADIUM CATALYZED RING CLOSURE OF TRIAZOLYL TRYPTAMINE MERCK & CO INC (US) 2003-10-15 EP disclosed
EP-0925302-B1 PALLADIUM CATALYZED INDOLIZATION MERCK & CO INC (US) 2002-11-20 EP disclosed
US-5808064-A HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE MERCK & CO., INC. (US) 1998-09-15 US disclosed
US-5567824-A CATALYZING THE CYCLIZATION IN PRESENCE OF A SOLVENT AND A PROTON ACCEPTOR MERCK & CO., INC. (US) 1996-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083759-A1 Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders BDNF, NTRK2, GRIN2A HTR2A 33/4885HTR1A 34/4885HTR6 68/4885
US-20200345585-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness SLC38A7, QPCT, SLC18A3 HTR2A 2029/4885HTR1A 1984/4885HTR6 1812/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A HTR2A 14/4885HTR1A 9/4885HTR6 15/4885
US-20220160737-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF HTR2A 11/4885HTR1A 13/4885HTR6 2/4885
US-20260090957-A1 Process for making aqueous therapeutic particle having stable exterior water clustering with nanosized thickness QPCT, SLC38A7, QPCTL HTR2A 2610/4885HTR1A 2572/4885HTR6 2030/4885
US-20220152088-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC10A1, SLC5A6, MC2R HTR2A 2775/4885HTR1A 2998/4885HTR6 1130/4885
US-11534454-B2 Complexing agent salt formulations of pharmaceutical compounds SLC10A1, SLC5A6, MC2R HTR2A 2775/4885HTR1A 2998/4885HTR6 1130/4885
US-20260108544-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH HTR1B, HTR6, BDNF HTR2A 9/4885HTR1A 11/4885HTR6 2/4885
US-20260053831-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION HTR1B, HTR2B, HTR3B HTR2A 9/4885HTR1A 7/4885HTR6 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.