Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.30 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894142 | 0.79 | RIPK1 (0.36) | RIPK1HTR2A | |
| SCHEMBL17286544 | 0.74 | ELANE (0.57) | ELANECA2RIPK1MTNR1AMTNR1B | |
| SCHEMBL12049350 | 0.73 | ELANE (0.44) | ELANECA2RIPK1KDM1A | |
| SCHEMBL6371292 | 0.73 | BCHE (0.41) | CA2RIPK1HTR2ANR1H2 | |
| SCHEMBL6375541 | 0.72 | KDM4E (0.34) | RIPK1 | |
| SCHEMBL17355754 | 0.69 | ELANE (0.54) | ELANECA2MTNR1AMTNR1BKDM1A | |
| SCHEMBL15447320 | 0.68 | ELANE (0.47) | ELANECA2KDM1A | |
| SCHEMBL17410677 | 0.68 | ELANE (0.51) | ELANECA2RIPK1MTNR1AMTNR1B | |
| SCHEMBL4061539 | 0.67 | ELANE (0.65) | ELANECA2KDM1A | |
| SCHEMBL13337964 | 0.67 | ELANE (0.46) | ELANECA2MAOBMAOARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153596-A1 | Novel thiourea derivatives and the pharmaceutical compositions containing the same | PACIFIC CORPORATION (KR) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153596-A1 | Novel thiourea derivatives and the pharmaceutical compositions containing the same | TAS2R40, TAS1R2, TAS2R45 | ELANE 1900/4885CA2 1239/4885RIPK1 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.