Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135480 | 1.00 | GPR88 (0.46) | GPR88RAB9AHPGDLMNAFAAH | |
| SCHEMBL30344053 | 0.85 | ALDH1A1 (0.50) | RAB9AHPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL29676847 | 0.79 | CTSS (0.49) | ALDH1A1 | |
| SCHEMBL4838542 | 0.79 | CTSS (0.49) | ALDH1A1 | |
| SCHEMBL4838536 | 0.79 | CTSS (0.49) | ALDH1A1 | |
| SCHEMBL4704028 | 0.79 | CTSS (0.49) | ALDH1A1 | |
| SCHEMBL5500456 | 0.76 | MMEL1 (0.48) | RAB9AHPGDLMNAFAAHSMN1; SMN2 | |
| SCHEMBL18765605 | 0.76 | ALDH1A1 (0.46) | MAPK1ALDH1A1 | |
| SCHEMBL16396348 | 0.76 | ALDH1A1 (0.46) | MAPK1ALDH1A1 | |
| SCHEMBL16137776 | 0.76 | MAPT (0.41) | RAB9AHPGDLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289950-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096296-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |