Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950108 | 0.92 | ALDH1A1 (0.48) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL6201817 | 0.91 | PRSS1 (0.58) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL7138097 | 0.85 | HDAC1 (0.44) | HDAC1ALDH1A1TSHRFOLH1 | |
| SCHEMBL1319907 | 0.84 | LMNA (0.64) | PLA2G2APLA2G10LMNAHDAC1KMT2A | |
| SCHEMBL1290930 | 0.84 | KMT2A (0.58) | PLA2G2APLA2G10LMNACA1CA2 | |
| SCHEMBL13240462 | 0.82 | ALDH1A1 (0.62) | PLA2G2ALMNAKMT2AALDH1A1TSHR | |
| SCHEMBL7789337 | 0.80 | ALDH1A1 (0.55) | CA1CA2CA9HDAC6KMT2A | |
| SCHEMBL1296450 | 0.79 | CA1 (0.63) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL39676 | 0.79 | TSHR (0.47) | CA1CA2ALDH1A1TSHRFOLH1 | |
| SCHEMBL29472003 | 0.79 | TSHR (0.47) | CA1CA2ALDH1A1TSHRFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6503632-B1 | Siloxane polymers typified by polydimethylsiloxane have excellent biocompatibility, gas permeability, etc. alkylamide groups impart strength; medical equipment | NOF CORPORATION (JP) | 2003-01-07 | — | — | US | disclosed |
| EP-1116740-A1 | POLYDIALKYLSILOXANE / POLYAMIDE COPOLYMER, PROCESS FOR PRODUCING THE SAME, AND VARIOUS MATERIALS | NOF CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| EP-0510003-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES. | PFIZER LTD (GB) | 1992-10-28 | — | — | EP | disclosed |