Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.51 |
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22649095 | 0.83 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27843942 | 0.83 | HPGD (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27824953 | 0.82 | HPGD (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4496081 | 0.81 | ALDH1A1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4495899 | 0.81 | AMY1A (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30863444 | 0.81 | ALDH1A1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL57009 | 0.81 | POLB (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10826360 | 0.81 | KDM4E (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8593391 | 0.80 | HPGD (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27843966 | 0.80 | HPGD (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003060099-A2 | METHODS AND APPARATUS FOR SPINNING SPIDER SILK PROTEIN | NEXIA BIOTECHNOLOGIES, INC. (CA) | 2003-07-24 | — | — | WO | disclosed |
| US-5965065-A | USING A FREESTANDING, THIN FILM OF A POLYMER, METAL-POLYMER COMPOSITE, MESH-SUPPORTED POLYMER FILM, OR MESH-SUPPORTED METAL-POLYMER COMPOSITE; POLYBENZIMIDAZOLES | POWELL STEPHEN FORBES (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0354040-A2 | Membranes prepared from blends of polybenzimidazole with polyarylates | HOECHST CELANESE CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |
| US-4842740-A | LESS SUSCEPTIBLE TO MOISTURE AND MORE THERMALLY PROCESSABLE | HOECHST CELANESE CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |