SCHEMBL7136409

SCHEMBL7136409

CC(C)(C)c1ccc(C(C)(C)C)c(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.41
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALOX15 P16050 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAPT P10636 1/20 0.38
ATP2A2 P16615 1/20 0.38
ATP2A3 Q93084 1/20 0.38
TYR P14679 3/20 0.36
LMNA P02545 2/20 0.36
NR1I2 O75469 1/20 0.36
CYP2C9 P11712 1/20 0.36
MIF P14174 1/20 0.36
HTT P42858 1/20 0.36
NFE2L2 Q16236 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11357992 0.86 GABRA1 (0.38) CA2ALDH1A1TSHRTDP1ALOX15
SCHEMBL136457 0.84 CA2 (0.32) CA2ALDH1A1TSHRTDP1
SCHEMBL31289647 0.84 CA2 (0.32) CA2ALDH1A1TSHRTDP1
SCHEMBL5910979 0.84 CA2 (0.32) CA2ALDH1A1TSHRTDP1
SCHEMBL6061735 0.84 CA2 (0.32) CA2ALDH1A1TSHRTDP1MAPT
SCHEMBL142313 0.84 ALDH1A1 (0.48) CA2ALDH1A1TSHRTDP1ALOX15
SCHEMBL1322769 0.84 CA2 (0.32) CA2ALDH1A1TSHRTDP1
SCHEMBL11747935 0.82 CA2 (0.31) CA2ALDH1A1TSHRTDP1
Ammonia Solution, Strong SCHEMBL478297 0.82 ALDH1A1 (0.46) CA2ALDH1A1TSHRTDP1ALOX15
SCHEMBL304569 0.80 CA2 (0.57) CA2ALDH1A1TSHRTDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6503662-B1 Tert-butylbenzene derivative prevents oxidation and decomposition of solvent at the time of charging which causes decreased battery characteristics UBE INDUSTRIES, LTD. (JP) 2003-01-07 US claimed