SCHEMBL7136641

SCHEMBL7136641

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nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
CYP2D6 P10635 1/20 0.58
ALOX15 P16050 1/20 0.58
PAM P19021 1/20 0.38
GABRR1 P24046 2/20 0.31
GABRR2 P28476 2/20 0.31
BLM P54132 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
APEX1 P27695 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20505819 1.00 ALDH1A1 (0.58) ALDH1A1CYP2D6ALOX15PAMGABRR1
SCHEMBL7136638 1.00 ALDH1A1 (0.58) ALDH1A1CYP2D6ALOX15PAMGABRR1
SCHEMBL20505388 0.83 ALDH1A1 (0.41) ALDH1A1CYP2D6ALOX15
Glutaconate SCHEMBL12230 0.77
Glutaconate SCHEMBL2514167 0.77 ALDH1A1 (0.65) ALDH1A1CYP2D6ALOX15PAMGABRR1
Glutaconate SCHEMBL688877 0.77
Glutaconate SCHEMBL21841 0.77
SCHEMBL213024 0.75 CYP2D6 (1.00) ALDH1A1CYP2D6ALOX15PAMGABRR1
SCHEMBL190067 0.75 CYP2D6 (1.00) ALDH1A1CYP2D6ALOX15PAMGABRR1
SCHEMBL3134391 0.75 CYP2D6 (1.00) ALDH1A1CYP2D6ALOX15PAMGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260009056-A1 PRODUCTION OF CHEMICALS FROM RENEWABLE SOURCES ZYMOCHEM INC (US) 2026-01-08 US disclosed
US-12258610-B2 Production of chemicals from renewable sources ZYMOCHEM, INC. (US) 2025-03-25 US disclosed
US-12084704-B2 Methods for producing isobutene from 3-methylcrotonic acid GLOBAL BIOENERGIES (FR) 2024-09-10 US disclosed
CN-110914441-B Improved process for producing isobutene from 3-methylcrotonic acid 环球生物能源公司 2024-06-28 CN disclosed
EP-3622080-B1 IMPROVED METHODS FOR PRODUCING ISOBUTENE FROM 3-METHYLCROTONIC ACID GLOBAL BIOENERGIES (FR) 2024-03-27 EP disclosed
US-11692208-B2 Production of chemicals from renewable sources ZYMOCHEM, INC. (US) 2023-07-04 US disclosed
US-20230109883-A1 PRODUCTION OF CHEMICALS FROM RENEWABLE SOURCES ZYMOCHEM, INC. 2023-04-13 US disclosed
US-20220372528-A1 PRODUCTION OF CHEMICALS FROM RENEWABLE SOURCES ZYMOCHEM, INC. 2022-11-24 US disclosed
US-20210403956-A1 METHODS FOR PRODUCING ISOBUTENE FROM 3-METHYLCROTONIC ACID GLOBAL BIOENERGIES (FR) 2021-12-30 US disclosed
US-11124806-B2 Methods for producing isobutene from 3-methylcrotonic acid GLOBAL BIOENERGIES (FR) 2021-09-21 US disclosed
EP-3599246-A1 MEANS AND METHODS FOR SYNTHESIZING PRECURSORS OF Y-AMINOBUTYRIC ACID (GABA) ANALOGS RIJKSUNIVERSITEIT GRONINGEN (NL) 2020-01-29 EP disclosed
EP-3535281-A1 FUSION POLYPEPTIDES Oxford University Innovation Limited (GB) 2019-09-11 EP disclosed
US-20190255167-A1 FUSION POLYPEPTIDES UNIV OXFORD INNOVATION LTD (GB) 2019-08-22 US disclosed
US-20180371503-A1 METHODS FOR PRODUCING ISOBUTENE FROM 3-METHYLCROTONIC ACID GLOBAL BIOENERGIES (FR) 2018-12-27 US disclosed
EP-3377639-A2 METHODS FOR PRODUCING ISOBUTENE FROM 3-METHYLCROTONIC ACID Global Bioenergies (FR) 2018-09-26 EP disclosed
WO-2003065979-A2 METHODS OF DIAGNOSIS, MONITORING AND TREATMENT OF FERTILITY NORTH SHORE-LONG ISLAND JEWISH RESEARCH INSTITUTE (US) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009056-A1 PRODUCTION OF CHEMICALS FROM RENEWABLE SOURCES HPD, PGD, ADSL ALDH1A1 200/4885CYP2D6 485/4885ALOX15 353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.