Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24581535 | 0.72 | TNK2 (0.37) | MEN1KMT2ATNK2ITGB1ITGA4 | |
| SCHEMBL28503 | 0.72 | MEN1 (0.38) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3500438 | 0.71 | TNK2 (0.44) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1531846 | 0.70 | MEN1 (0.61) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11767308 | 0.70 | ELANE (0.52) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL739210 | 0.69 | DHFR (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2TNK2 | |
| SCHEMBL7860591 | 0.69 | MEN1 (0.45) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL217929 | 0.69 | TNK2 (0.43) | MEN1KMT2AALDH1A1TNK2ACP1 | |
| SCHEMBL20032688 | 0.69 | MEN1 (0.40) | MEN1KMT2ATNK2SLC6A3 | |
| SCHEMBL1186911 | 0.69 | MEN1 (0.52) | MEN1KMT2ALMNASMN1; SMN2TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670346-B1 | Treatment and/or inhibition of the development of osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia or atherosclerosis in susceptible warm-blooded animals including humans, administering selective estrogen | ENDORECHERCHE, INC. (CA) | 2003-12-30 | — | — | US | disclosed |