Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 3/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138342 | 0.89 | ALDH1A1 (0.53) | KDM1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7138252 | 0.87 | ERBB2 (0.45) | KDM1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5363090 | 0.85 | LRRK2 (0.60) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL5366009 | 0.85 | ERBB2 (0.62) | KDM1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7137722 | 0.84 | KDM1A (0.54) | KDM1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5357895 | 0.84 | IGF1R (0.53) | KDM1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5366852 | 0.84 | LRRK2 (0.50) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL7136800 | 0.83 | MAP1LC3B (0.56) | MEN1KMT2AMAPTTDP1PLK4 | |
| SCHEMBL5358747 | 0.83 | PLK4 (0.60) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7137544 | 0.82 | LRRK2 (0.49) | MEN1KMT2AMAPTTDP1PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506763-B2 | Useful in prevention and treatment of protein kinase related disorders such as cancer | SUGEN, INC. | 2003-01-14 | — | — | US | disclosed |