Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | AHCY | P23526 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GNMT | Q14749 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13208057 | 1.00 | LMNA (0.59) | LMNAADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL13208052 | 0.89 | LMNA (0.59) | LMNAADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7131480 | 0.89 | LMNA (0.59) | LMNAADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL13898193 | 0.80 | ADORA3 (0.62) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL20482906 | 0.78 | LMNA (0.64) | LMNAADORA3ADORA2AADORA2BCYP1A2 | |
| SCHEMBL31160178 | 0.78 | LMNA (0.79) | LMNAADORA2AADORA2BCYP1A2 | |
| SCHEMBL17706392 | 0.78 | ADORA3 (0.65) | ADORA3ADORA2AADORA1 | |
| SCHEMBL7715231 | 0.77 | HIF1A (0.57) | LMNAHIF1A | |
| SCHEMBL31160186 | 0.76 | LMNA (0.66) | LMNAADORA2AADORA2BCYP1A2HIF1A | |
| SCHEMBL20149800 | 0.75 | LMNA (0.61) | LMNAADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506896-B1 | Conjugated to peptides, proteins, nucleic acids, antibodies, RNA, or DNA; medical diagnosis, electronics | NANOGEN RECOGNOMICS GMBH (DE) | 2003-01-14 | — | — | US | disclosed |