Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.55 |
| ▸ | ITGAV | P06756 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315916 | 1.00 | EEF2K (0.69) | EEF2KL3MBTL1ALDH1A1ATMCA2 | |
| SCHEMBL13418142 | 0.88 | EEF2K (0.61) | EEF2KL3MBTL1ALDH1A1ATMCA2 | |
| SCHEMBL7146586 | 0.86 | ALDH1A1 (0.73) | EEF2KL3MBTL1ALDH1A1ATMCA2 | |
| SCHEMBL28404274 | 0.82 | ATM (0.76) | EEF2KL3MBTL1ALDH1A1ATMITGB3 | |
| SCHEMBL28405808 | 0.82 | EEF2K (1.00) | EEF2KL3MBTL1CA2MMP2CA12 | |
| SCHEMBL6772863 | 0.81 | EEF2K (0.66) | EEF2KL3MBTL1ALDH1A1ATMITGB3 | |
| SCHEMBL7144205 | 0.80 | EEF2K (0.64) | EEF2KL3MBTL1ALDH1A1ATMITGB3 | |
| SCHEMBL3839370 | 0.79 | ALDH1A1 (0.76) | EEF2KL3MBTL1ALDH1A1ATMCA2 | |
| SCHEMBL3310158 | 0.79 | EEF2K (0.66) | EEF2KL3MBTL1ALDH1A1ATMITGB3 | |
| SCHEMBL644240 | 0.79 | EEF2K (0.66) | EEF2KL3MBTL1ALDH1A1ATMITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107903185-B | Preparation and application of novel eEF2K inhibitor | 四川大学 | 2020-05-26 | — | — | CN | disclosed |
| EP-0928790-B1 | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2003-03-05 | — | — | EP | disclosed |
| US-6344562-B1 | ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. | 2002-02-05 | — | — | US | disclosed |
| US-20020010316-A1 | Thiazole derivatives | ALIG LEO (CH) | 2002-01-24 | — | — | US | disclosed |
| US-6320054-B1 | INHIBIT BINDING OF ADHESIVE PROTEINS TO THE SURFACE OF DIFFERENT TYPES F CELL AND ACCORDINGLY INFLUENCE CELL-CELL AND CELL-MATRIX INTERACTIONS. | HOFFMAN-LA ROCHE INC. | 2001-11-20 | — | — | US | disclosed |
| US-6100282-A | Thiazole derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-08-08 | — | — | US | disclosed |
| EP-0928790-A1 | Thiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010316-A1 | Thiazole derivatives | VCAM1, SOST, TGFB1 | EEF2K 1935/4885L3MBTL1 1072/4885ALDH1A1 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.