Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141190 | 0.76 | KMT2A (0.46) | KMT2ASMN1; SMN2ALDH1A1POLBTDP1 | |
| SCHEMBL28588859 | 0.75 | EHMT2 (0.47) | KMT2AEHMT2EHMT1APOBEC3GSMN1; SMN2 | |
| SCHEMBL7133969 | 0.75 | EHMT2 (0.47) | KMT2AEHMT2EHMT1APOBEC3GSMN1; SMN2 | |
| SCHEMBL31487780 | 0.72 | KMT2A (0.58) | KMT2ASMN1; SMN2ALDH1A1FAAHPRSS1 | |
| SCHEMBL10848414 | 0.71 | KMT2A (0.61) | KMT2ASMN1; SMN2ALDH1A1FAAHPRSS1 | |
| SCHEMBL27300181 | 0.69 | KMT2A (0.63) | KMT2ASMN1; SMN2FAAHPRSS1PRSS2 | |
| SCHEMBL7140571 | 0.69 | EHMT2 (0.40) | KMT2AEHMT2EHMT1APOBEC3GSMN1; SMN2 | |
| SCHEMBL7140573 | 0.68 | ALDH1A1 (0.49) | KMT2AEHMT2EHMT1APOBEC3GSMN1; SMN2 | |
| SCHEMBL1360606 | 0.67 | EHMT2 (0.61) | KMT2AEHMT2EHMT1APOBEC3GALDH1A1 | |
| SCHEMBL1972890 | 0.67 | KMT2A (0.65) | KMT2ASMN1; SMN2FAAHPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086124-B1 | NOVEL CYCLOSPORINS | CHEM AG C (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-6583265-B1 | Compound for use in the prevention of viral and bacterial infections | C-CHEM AG (CH) | 2003-06-24 | — | — | US | disclosed |