Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140577 | 0.76 | KMT2A (0.45) | KMT2APRSS1PRSS2PRSS3CA1 | |
| SCHEMBL1972890 | 0.68 | KMT2A (0.65) | KMT2APRSS1PRSS2PRSS3CA1 | |
| SCHEMBL29482080 | 0.68 | TSHR (0.58) | KMT2ACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7141184 | 0.67 | ALDH1A1 (0.39) | KMT2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27300181 | 0.67 | KMT2A (0.63) | KMT2APRSS1PRSS2PRSS3CA1 | |
| SCHEMBL28029593 | 0.66 | ALDH1A1 (0.41) | KMT2ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3936439 | 0.66 | KMT2A (0.57) | KMT2APRSS1PRSS2PRSS3CA1 | |
| SCHEMBL11438308 | 0.66 | KMT2A (0.57) | KMT2APRSS1PRSS2PRSS3CA1 | |
| SCHEMBL10848414 | 0.66 | KMT2A (0.61) | KMT2APRSS1PRSS2PRSS3CA1 | |
| SCHEMBL9344000 | 0.65 | KMT2A (0.61) | KMT2APRSS1PRSS2PRSS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086124-B1 | NOVEL CYCLOSPORINS | CHEM AG C (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-6583265-B1 | Compound for use in the prevention of viral and bacterial infections | C-CHEM AG (CH) | 2003-06-24 | — | — | US | disclosed |
| EP-1086124-A1 | NOVEL CYCLOSPORINS | C-Chem AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065933-A1 | NOVEL CYCLOSPORINS | C-CHEM AG (CH) | 1999-12-23 | — | — | WO | disclosed |